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Ligand

NameCHEMBL483993
Molecular formulaC22H31N5O3
IUPAC name8-(4-methoxy-2,5-dimethylphenyl)-N,N-bis(2-methoxyethyl)-2,7-dimethylpyrazolo[1,5-a][1,3,5]triazin-4-amine
Molecular weight413.522
Hydrogen bond acceptor7
Hydrogen bond donor0
XlogP3.4
SynonymsBDBM29464
Pyrazolo[1,5-a]-1,3,5-triazine, 12-33
Inchi KeyRPKIJOOZVCXURK-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H31N5O3/c1-14-13-19(30-7)15(2)12-18(14)20-16(3)25-27-21(20)23-17(4)24-22(27)26(8-10-28-5)9-11-29-6/h12-13H,8-11H2,1-7H3
PubChem CID42618195
ChEMBLCHEMBL483993
IUPHARN/A
BindingDB29464
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
301926Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
301922Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
301921Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
301925Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
301919Corticotropin-releasing factor receptor 1P35353Crhr1Rattus norvegicus (Rat)415
301923Corticotropin-releasing factor receptor 1P34998CRHR1Homo sapiens (Human)444
301918Corticotropin-releasing factor receptor 2Q13324CRHR2Homo sapiens (Human)411
301920D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
301927D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
301924Vasopressin V1a receptorP37288AVPR1AHomo sapiens (Human)418

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