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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TIPP-psi
Molecular formula	C37H40N4O5
IUPAC name	(2S)-2-[[(2S)-2-[[(3S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-3,4-dihydro-1H-isoquinolin-3-yl]methylamino]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid
Molecular weight	620.75
Hydrogen bond acceptor	7
Hydrogen bond donor	5
XlogP	2.3
Synonyms	TIPP-\|. 159992-07-1 DTXSID40415533 AC1NSKPF TIPP(psi) CHEMBL3038183 TIPPpsi GTPL1637 BDBM85328 (2S)-2-[[(2S)-2-[[(3S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-3,4-dihydro-1H-isoquinolin-3-yl]methylamino]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid D00BXG H-Tyr-Tic(CH2NH)-Phe-Phe-OH [ Show all ]
Inchi Key	RPKMHCAOERKVEC-DYTOPAQESA-N
Inchi ID	InChI=1S/C37H40N4O5/c38-32(19-27-15-17-31(42)18-16-27)36(44)41-24-29-14-8-7-13-28(29)22-30(41)23-39-33(20-25-9-3-1-4-10-25)35(43)40-34(37(45)46)21-26-11-5-2-6-12-26/h1-18,30,32-34,39,42H,19-24,38H2,(H,40,43)(H,45,46)/t30-,32-,33-,34-/m0/s1
PubChem CID	5311481
ChEMBL	CHEMBL3038183
IUPHAR	1637
BindingDB	85328
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
301935	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
301938	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
301939	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
461808	Delta-type opioid receptor	P79291	OPRD1	Sus scrofa (Pig)	228
301934	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
301936	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
301937	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
301940	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
556666	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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