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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431123
Molecular formula	C25H33N5O3
IUPAC name	2-[6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazolin-2-yl]-N,N-dimethylethanamine
Molecular weight	451.571
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50440781 MLS-0471472.0001 SCHEMBL15819631
Inchi Key	RRQMTTVLMMRAEF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H33N5O3/c1-28(2)11-10-24-26-19-17-23(33-5)22(32-4)16-18(19)25(27-24)30-14-12-29(13-15-30)20-8-6-7-9-21(20)31-3/h6-9,16-17H,10-15H2,1-5H3
PubChem CID	56593274
ChEMBL	CHEMBL2431123
IUPHAR	N/A
BindingDB	50440781
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
303448	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
303447	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
303446	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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