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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL195534
Molecular formula	C20H24N2O
IUPAC name	1-(6-amino-2,2,4-trimethyl-4-phenyl-3H-quinolin-1-yl)ethanone
Molecular weight	308.425
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.6
Synonyms	1-(6-amino-2,2,4-trimethyl-4-phenyl-3,4-dihydroquinolin-1(2H)-yl)ethanone AKOS021993566 Oprea1_660841 1-acetyl-6-amino-4-phenyl-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline BDBM50410305 DivK1c_004124 SCHEMBL1322285 AC1MDHVC CDS1_003084 MCULE-1669012183 ST50987400 1-(6-amino-2,2,4-trimethyl-4-phenyl-3H-quinolin-1-yl)ethanone BAS 01520500 ChemDiv1_022860 Oprea1_724117 332904-33-3 BIM-0015308.P001 EU-0006731 SR-01000450228 1-(6-Amino-2,2,4-trimethyl-4-phenyl-3,4-dihydro-2H-quinolin-1-yl)-ethanone AKOS000622291 MolPort-001-905-575 STK093961 1-acetyl-6-amino-2,2,4-trimethyl-4-phenyl-1,2,3,4-tetrahydroquinoline BBL015609 CTK7D8345 RTWPATFTOPMBPW-UHFFFAOYSA-N CBMicro_015198 HMS651P02 SR-01000450228-1 [ Show all ]
Inchi Key	RTWPATFTOPMBPW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H24N2O/c1-14(23)22-18-11-10-16(21)12-17(18)20(4,13-19(22,2)3)15-8-6-5-7-9-15/h5-12H,13,21H2,1-4H3
PubChem CID	2837084
ChEMBL	CHEMBL195534
IUPHAR	N/A
BindingDB	50410305
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
305015	Follicle-stimulating hormone receptor	P23945	FSHR	Homo sapiens (Human)	695

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