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Ligand

Name8-Cyclopentyl-1,3-dimethylxanthine
Molecular formulaC12H16N4O2
IUPAC name8-cyclopentyl-1,3-dimethyl-7H-purine-2,6-dione
Molecular weight248.286
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP1.6
SynonymsKBio2_000831
Lopac0_000391
NCGC00015178-03
NCGC00093819-04
1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-1,3-dimethyl-
[ Show all ]
Inchi KeySCVHFRLUNIOSGI-UHFFFAOYSA-N
Inchi IDInChI=1S/C12H16N4O2/c1-15-10-8(11(17)16(2)12(15)18)13-9(14-10)7-5-3-4-6-7/h7H,3-6H2,1-2H3,(H,13,14)
PubChem CID1917
ChEMBLCHEMBL106265
IUPHAR385
BindingDB81925
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 11
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
311161Adenosine receptor A1P25099Adora1Rattus norvegicus (Rat)326
311163Adenosine receptor A1P34970ADORA1Oryctolagus cuniculus (Rabbit)328
311164Adenosine receptor A1P47745ADORA1Cavia porcellus (Guinea pig)326
311167Adenosine receptor A1P28190ADORA1Bos taurus (Bovine)326
554801Adenosine receptor A1P30542ADORA1Homo sapiens (Human)326
311168Adenosine receptor A2aP29274ADORA2AHomo sapiens (Human)412
311165Adenosine receptor A3P35342ADORA3Ovis aries (Sheep)317
311169Adenosine receptor A3P0DMS8ADORA3Homo sapiens (Human)318
311162D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
311171Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
311170P2Y purinoceptor 2P58825P2RY2Cricetulus griseus (Chinese hamster)166

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