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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	MDMA
Molecular formula	C11H15NO2
IUPAC name	1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine
Molecular weight	193.246
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.2
Synonyms	69610-10-2 CHEMBL43048 DivK1c_000962 I14-2777 MDMA (unspecified) NCGC00168266-01 SCHEMBL44210 (+/-)-MDMA solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material 3,4-Methylenedioxy-N,alpha-dimethyl-beta-phenylethylamine BDBM50010588 D0F5NJ Ecstasy (Drug) KE1SEN21RM Midomafetamine PDSP1_001522 XTC (+-)-(3,4-Methylenedioxy)methamphetamine 1,3-Benzodioxole-5-ethanamine, N,alpha-dimethyl- 3,4-methylenedioxymethylamphetamine CHEBI:1391 DB01454 GTPL4574 Mandy [Street Name] N,alpha-Dimethyl-1,3-benzodioxole-5-ethanamine rac-3,4-Methylenedioxymethamphetamine (+/-)-(3,4-Methylenedioxy)methamphetamine 1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine 54946-52-0 AC1L1BUR CTK5D0599 DL-(3,4-Methylenedioxy)methamphetamine IDI1_000962 Methylenedioxy Methamphetamine NCGC00168266-02 SHXWCVYOXRDMCX-UHFFFAOYSA-N (RS)-3,4-(methylenedioxy)methamphetamine 3,4-Methylenedioxy-N-methylamphetamine (MDMA) C07577 D11172 Epitope ID:178091 LS-34695 Midomafetamine (USAN/INN) PDSP2_001506 XTC [Street Name] (+-)-N-Methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane 1,3-Benzodioxole-5-ethanamine,N,a-dimethyl- 42542-10-9 DEA No. 7405 HSDB 6929 N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE rac-MDMA (rac-3,4-Methylenedioxymethamphetamine) 1.0 mg/ml in Methanol (+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE 3,4-MDMA 64057-70-1 (hydrochloride) AKOS006283463 D0EX3I Ecstasy KBio1_000962 Methylenedioxymethamphetamine NINDS_000962 UNII-KE1SEN21RM ( inverted exclamation markA)-1,3-benzodioxolyl-N-methyl-2-propanamine( inverted exclamation markA)-3,4-methylenedioxy-N-methyl-\|A-methyl-2-phenethylamineDL-3,4-methylenedioxy-N-methylamphetaminemethylenedioxymethamphetamine 3,4-methylenedioxymethamphetamine CCRIS 9277 FT-0693477 LS-34696 Midomafetamine [USAN] Phenethylamine, N,alpha-dimethyl-3,4-methylenedioxy- [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](methyl)amine (+-)-N-Methyl-3,4-(methylenedioxy)amphetamine 1-(1,3-Benzodioxol-5-yl)-N-methyl-2-propanamine [ Show all ]
Inchi Key	SHXWCVYOXRDMCX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3
PubChem CID	1615
ChEMBL	CHEMBL43048
IUPHAR	N/A
BindingDB	50010588
DrugBank	DB01454
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
314780	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
314803	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
314792	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
314776	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
314787	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
556733	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
314775	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
314779	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
314805	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
314804	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
314774	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
314797	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
314773	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
314769	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
314782	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
314789	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
314781	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
314791	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
314793	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
314800	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413