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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	cyclopentolate
Molecular formula	C17H25NO3
IUPAC name	2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate
Molecular weight	291.391
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.7
Synonyms	Ciclopentolato [INN-Spanish] Cyclopentolate (INN) IDI1_000610 (+/-)-cyclopentolate L000802 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenyl-acetate NINDS_000610 AB00053445 SBI-0051324.P003 AN-34337 Spectrum5_000793 Benzeneacetic acid, .alpha.-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl ester BSPBio_002097 CAS_512-15-2 Cyclogyl Cyclopentolatum [INN-Latin] DivK1c_000610 KBio2_003904 1-Hydroxy-.alpha.-phenylcyclopentaneacetic acid, 2-(dimethylamino)ethyl ester Minims Cyclopentolate 2-Dimethylaminoethyl 2-(1-hydroxycyclopentyl)-2-phenylacetat Prestwick0_001095 AC1L1EQK SPBio_000983 b-dimethylaminoethyl(1-hydroxycyclopentyl)phenylacetate beta-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate CHEMBL1201338 Cyclopentoiate D07759 FT-0624265 (+)-alpha-(1-Hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester KBioGR_000886 2-(Dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate # Mydrilate (Salt/Mix) 512-15-2 Prestwick3_001095 AKOS015962137 Spectrum3_000369 Bell Pentolate BRD-A77291778-003-15-4 CTK8H5258 Cyclopentolate [INN:BAN] DB00979 KBio1_000610 (?)-alpha-(1-Hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester LS-175236 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate NSC_2905 AB00053445_12 SCHEMBL132500 API0009075 Spectrum_000856 Benzeneacetic acid, alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl ester C-23922 CC-26105 Cyclogyl (Salt/Mix) Cyclopentylate DTXSID3048528 KBio2_006472 1-hydroxy-alpha-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester MolPort-005-935-560 2-dimethylaminoethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate Prestwick1_001095 AC1Q67OG SPBio_003055 BCP21334 BPBio1_001288 Ciclopentolato D0B1EV GTPL7153 (+-)-cyclopentolate KBioSS_001336 2-(Dimethylamino)ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate NCGC00018213-02 s114 alpha-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester Spectrum4_000303 Bell Pentolate (TN) BSPBio_001170 C06932 cyclo-pentolatum Cyclopentolatum Diopentolate KBio2_001336 .beta.-(Dimethylamino)ethyl (1-hydroxycyclopentyl)phenylacetate M-1318 2-Dimethylaminoethyl 1-hydroxy-.alpha.-phenylcyclopentaneacetate Ocu-Pentolate AC-15991 SKYSRIRYMSLOIN-UHFFFAOYSA-N AS-16057 STL430452 beta-(Dimethylamino)ethyl (1-hydroxycyclopentyl)phenylacetate CHEBI:4024 Cyclopentaneacetic acid, 1-hydroxy-.alpha.-phenyl-, 2-(dimethylamino)ethyl ester Cylate EINECS 208-136-4 KBio3_001317 2-(Dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate Mydrilate 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid beta-(dimethylamino)ethyl ester Prestwick2_001095 ACM512152 Spectrum2_001122 BDBM82375 BRD-A77291778-003-05-5 [ Show all ]
Inchi Key	SKYSRIRYMSLOIN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3
PubChem CID	2905
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82375
DrugBank	DB00979
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
316928	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
316931	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
316929	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
316927	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
316930	Muscarinic acetylcholine receptor M4	P17200	CHRM4	Gallus gallus (Chicken)	490

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