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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1774043
Molecular formula	C34H29FN4O4
IUPAC name	3-[4-[4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphenyl)pyrimidine-2-carbonyl]piperazin-1-yl]naphthalene-1-carboxylic acid
Molecular weight	576.628
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50343721 3-(4-(4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphenyl)pyrimidine-2-carbonyl)piperazin-1-yl)-1-naphthoic acid
Inchi Key	SLFCKQWVMXDHDU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H29FN4O4/c1-21-7-12-27(30(35)17-21)31-29(22-8-10-25(43-2)11-9-22)20-36-32(37-31)33(40)39-15-13-38(14-16-39)24-18-23-5-3-4-6-26(23)28(19-24)34(41)42/h3-12,17-20H,13-16H2,1-2H3,(H,41,42)
PubChem CID	46869398
ChEMBL	CHEMBL1774043
IUPHAR	N/A
BindingDB	50343721
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
317109	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
317107	Cholecystokinin receptor type A	P32238	CCKAR	Homo sapiens (Human)	428
317108	Cholecystokinin receptor type A	O08786	Cckar	Mus musculus (Mouse)	436
317110	Gastrin/cholecystokinin type B receptor	P32239	CCKBR	Homo sapiens (Human)	447

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