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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL446892
Molecular formula	C23H23F3N2O
IUPAC name	1-[(1-phenylpyrrol-3-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperidin-4-ol
Molecular weight	400.445
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	1-(1-Phenyl-1H-pyrrol-3-ylmethyl)-4-(3-trifluoromethyl-phenyl)-piperidin-4-ol BDBM50048232 4-[3-(Trifluoromethyl)phenyl]-1-[(1-phenyl-1H-pyrrol-3-yl)methyl]piperidin-4-ol
Inchi Key	TVQJPTVBALUGFW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23F3N2O/c24-23(25,26)20-6-4-5-19(15-20)22(29)10-13-27(14-11-22)16-18-9-12-28(17-18)21-7-2-1-3-8-21/h1-9,12,15,17,29H,10-11,13-14,16H2
PubChem CID	10597114
ChEMBL	CHEMBL446892
IUPHAR	N/A
BindingDB	50048232
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
328558	D(2) dopamine receptor	P52702	DRD2	Chlorocebus aethiops (Green monkey)	443
328559	D(3) dopamine receptor	P52703	DRD3	Chlorocebus aethiops (Green monkey)	400
328557	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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