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Ligand

NameRS-67506
Molecular formulaC18H28ClN3O4S
IUPAC nameN-[2-[4-[3-(4-amino-5-chloro-2-methoxyphenyl)-3-oxopropyl]piperidin-1-yl]ethyl]methanesulfonamide
Molecular weight417.949
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP1.7
SynonymsBDBM84951
D07OSA
PDSP1_001645
ZINC600432
1-[4-Amino-5-chloro-2-methoxyphenyl]-3-{1-[2-(methylsulfonyl) aminoethyl]-piperidin-4-yl}propan-1-one
[ Show all ]
Inchi KeyUATDVRSFFGFTAI-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H28ClN3O4S/c1-26-18-12-16(20)15(19)11-14(18)17(23)4-3-13-5-8-22(9-6-13)10-7-21-27(2,24)25/h11-13,21H,3-10,20H2,1-2H3
PubChem CID133076
ChEMBLCHEMBL83899
IUPHAR3230
BindingDB84951
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 15
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
3321725-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
5568295-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
3321675-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
3321665-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
3321705-hydroxytryptamine receptor 4Q62758Htr4Rattus norvegicus (Rat)406
5568285-hydroxytryptamine receptor 4O70528HTR4Cavia porcellus (Guinea pig)388
332169Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
332177Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
332176Alpha-2A adrenergic receptorP22909Adra2aRattus norvegicus (Rat)450
332171Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
332173Beta-1 adrenergic receptorP18090Adrb1Rattus norvegicus (Rat)466
462097Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
462096D(1A) dopamine receptorO77680DRD1Macaca mulatta (Rhesus macaque)446
332168Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
332174Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466

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