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Ligand

NameSch 58261
Molecular formulaC18H15N7O
IUPAC name4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
Molecular weight345.366
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP2.4
SynonymsLP01259
PDSP2_001183
SCHEMBL537287
[3H]-SCH 58261
2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
[ Show all ]
Inchi KeyUTLPKQYUXOEJIL-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H15N7O/c19-18-22-16-13(11-20-24(16)9-8-12-5-2-1-3-6-12)17-21-15(23-25(17)18)14-7-4-10-26-14/h1-7,10-11H,8-9H2,(H2,19,22)
PubChem CID176408
ChEMBLCHEMBL17127
IUPHAR431, 403
BindingDB50048466
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
345178Adenosine receptor A1P30542ADORA1Homo sapiens (Human)326
345180Adenosine receptor A1P28190ADORA1Bos taurus (Bovine)326
345181Adenosine receptor A1P25099Adora1Rattus norvegicus (Rat)326
345175Adenosine receptor A2aP29274ADORA2AHomo sapiens (Human)412
345176Adenosine receptor A2aP30543Adora2aRattus norvegicus (Rat)410
345179Adenosine receptor A2bP29275ADORA2BHomo sapiens (Human)332
345183Adenosine receptor A2bP29276Adora2bRattus norvegicus (Rat)332
345177Adenosine receptor A3P0DMS8ADORA3Homo sapiens (Human)318
345182D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446

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