Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

You can:

Ligand

Nameterazosin
Molecular formulaC19H25N5O4
IUPAC name[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone
Molecular weight387.44
Hydrogen bond acceptor8
Hydrogen bond donor1
XlogP1.4
SynonymsNCGC00025191-03
4097AH
SAM002589982
6,7-dimethoxy-2-{4-[(oxolan-2-yl)carbonyl]piperazin-1-yl}quinazolin-4-amine
Terazosin (INN)
[ Show all ]
Inchi KeyVCKUSRYTPJJLNI-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)
PubChem CID5401
ChEMBLCHEMBL611
IUPHAR7302
BindingDB50033111
DrugBankDB01162

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Total entries: 14
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
351654Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
351655Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
351663Alpha-1A adrenergic receptorO02824ADRA1AOryctolagus cuniculus (Rabbit)466
351665Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
351657Alpha-1B adrenergic receptorP18841ADRA1BMesocricetus auratus (Golden hamster)515
351660Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
351662Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
351653Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
351656Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
351658Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
351661Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
351666Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
351659Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
351664D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446

yangzhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218