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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL25220
Molecular formula	C22H19N5O3
IUPAC name	2,6-dimethyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methoxy]pyridine-3-carboxylic acid
Molecular weight	401.426
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.5
Synonyms	2,6-Dimethyl-4-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-nicotinic acid VJGPDUGNMPZEEE-UHFFFAOYSA-N 2,6-Dimethyl-4-[[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]oxy]pyridine-3-carboxylic acid BDBM50047123 2,6-dimethyl-4-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methoxy]pyridine-3-carboxylic acid SCHEMBL9177448 3-Carboxy-2,6-dimethyl-4-[2'-(tetrazol-5-yl)biphenyl-4-yl]methoxypyridine [ Show all ]
Inchi Key	VJGPDUGNMPZEEE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H19N5O3/c1-13-11-19(20(22(28)29)14(2)23-13)30-12-15-7-9-16(10-8-15)17-5-3-4-6-18(17)21-24-26-27-25-21/h3-11H,12H2,1-2H3,(H,28,29)(H,24,25,26,27)
PubChem CID	14950487
ChEMBL	CHEMBL25220
IUPHAR	N/A
BindingDB	50047123
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
356525	Type-1 angiotensin II receptor	Q9WV26	AGTR1	Cavia porcellus (Guinea pig)	359

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