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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL164931
Molecular formula	C24H24N6O2
IUPAC name	(4S,9R)-N-(2-aminoethyl)-24-hydroxy-3,10,14,16-tetrazahexacyclo[11.11.1.02,11.04,9.017,25.018,23]pentacosa-1(24),2,11,13,15,17(25),18,20,22-nonaene-12-carboxamide
Molecular weight	428.496
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	1.7
Synonyms	8N-(2-aminoethyl)-15-oxo-(9aR,13aS)-11,12,13,15-tetrahydro-10H-benzo[7,8]quinazolino[5,4-ab]phenazine-8-carboxamide 8N-(2-aminoethyl)-15-oxo-9a,10,11,12,13,13a,14,15-octahydro-9H-benzo[7,8]quinazolino[5,4-ab]phenazine-8-carboxamide BDBM50075921 N-(2-Aminoethyl)-5,6-[imino(cyclohexane-1beta,2beta-diyl)imino]-7-oxo-7H-benzo[e]perimidine-4-carboxamide
Inchi Key	WDYQSAPKHJAPBL-LSDHHAIUSA-N
Inchi ID	InChI=1S/C24H24N6O2/c25-9-10-26-24(32)18-20-16-17(21-22(18)30-15-8-4-3-7-14(15)29-21)23(31)13-6-2-1-5-12(13)19(16)27-11-28-20/h1-2,5-6,11,14-15,30-31H,3-4,7-10,25H2,(H,26,32)/t14-,15+/m0/s1
PubChem CID	135958361
ChEMBL	CHEMBL164931
IUPHAR	N/A
BindingDB	50075921
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
568872	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
568873	Corticotropin-releasing factor receptor 2	Q60748	Crhr2	Mus musculus (Mouse)	411

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