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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL186938
Molecular formula	C29H29ClF3NO3
IUPAC name	methyl 4-[4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanoate
Molecular weight	532.0
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	6.3
Synonyms	4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-butyric acid methyl ester BDBM50153613
Inchi Key	WEHXYCJSKSNRKW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H29ClF3NO3/c1-37-26(35)28(21-8-4-2-5-9-21,22-10-6-3-7-11-22)16-19-34-17-14-27(36,15-18-34)23-12-13-25(30)24(20-23)29(31,32)33/h2-13,20,36H,14-19H2,1H3
PubChem CID	44395286
ChEMBL	CHEMBL186938
IUPHAR	N/A
BindingDB	50153613
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
371333	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
371331	Nociceptin receptor	P35370	Oprl1	Rattus norvegicus (Rat)	367
371332	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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