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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	D-glutamic acid
Molecular formula	C5H9NO4
IUPAC name	(2R)-2-aminopentanedioic acid
Molecular weight	147.13
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-3.7
Synonyms	Lopac-G-2128 AJ-24146 NCGC00024501-03 BPBio1_001130 poly(D-glutamicacid) CS-6255 R-(?)-1-Aminopropane-1,3-dicarboxylic acid D-2-Aminopentanedioic acid SR-01000597732-1 D-Glutamicacid UNII-Q479989WEA delta-2-Aminoglutaric acid DGL G0057 (R)-2-Aminoglutaric acid Glutamic acid D-form 893G261 AC-15064 MFCD00063112 AM20100640 PDGA CAS-6893-26-1 Q-100774 D(-)-Glutamic acid, 99+% SBB006707 D-glutamate TC-066721 D-[14C]Glu ZINC895124 delta-Glutamate DSSTox_RID_82871 gammaDPGA (R)-2-aminopentanedioic acid H-D-Glu-OH KSC491O5N ACT08602 NCGC00024501-01 BDBM26431 PDSP2_000130 R-(-)-Glutamate D-2-Aminoglutaric acid SCHEMBL43222 D-Glutamic acid, >=99% (TLC) Tox21_113052 DB02517 delta-Glutaminic acid EN300-78764 (2R)-2-aminopentanedioicacid Glutamic acid # AB0010642 Lopac-gamma-2128 AK-47369 NCGC00024501-04 BR-47369 poly-D-gamma-glutamic acid CTK3J1756 RP21121 D-alpha-Aminoglutaric acid ST075000 D-Glutaminic acid WHUUTDBJXJRKMK-GSVOUGTGSA-N delta-2-Aminopentanedioate DSSTox_CID_28601 gamma-poly(D-glutamic acid) (R)-2-Aminoglutaric acid; (R)-2-Aminopentanedioic acid; D-Glu; R-(-)-1-Aminopropane-1,3-dicarboxylic acid Glutamic acid, D- AC-24113 MolPort-002-499-418 ANW-35567 PDSP1_000131 CHEBI:15966 Q479989WEA D-(-)-Glutamic acid SC-09473 TL806175 D0O1AK delta-Glutamic acid E620 glutamate (r)-glutamic acid HY-100805 L(+)-Glutamic acid AI3-09072 NCGC00024501-02 Biomol-NT_000169 PDSP2_001470 CHEMBL76232 R-(-)-Glutamic acid D-2-Aminopentanedioate SR-01000597732 D-Glutamic acid, Vetec(TM) reagent grade, >=99% UNII-61LJO5I15S component WHUUTDBJXJRKMK-GSVOUGTGSA-N delta-2-Aminoglutarate delta-Glutaminsaeure FT-0624571 (r)-1-aminopropane-1,3-dicarboxylic acid glutamic acid d- 6893-26-1 AB1001986 M02964 AKOS015854118 NSC 77686 C00217 PubChem10977 D(-)-Glutamic acid RTC-066721 D-Glu ST2406765 D-Glutaminsaeure Z-0144 delta-2-Aminopentanedioic acid DSSTox_GSID_48675 gamma-poly(D-glutamic acid) macromolecule (R)-2-aminopentanedioate GTPL4708 KS-00000A9T AC1L2M41 NCGC00015470-01 AS-12791 PDSP1_001486 CHEBI:53375 R-(-)-1-Aminopropane-1,3-dicarboxylic acid D-2-Aminoglutarate SC-49449 D-Glutamic acid, >=99% Tocris-0217 D0YB9P delta-Glutaminate EINECS 230-000-8 (2R)-2-aminopentanedioic acid GLUTAMIC ACID 138-16-9 [ Show all ]
Inchi Key	WHUUTDBJXJRKMK-GSVOUGTGSA-N
Inchi ID	InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
PubChem CID	23327
ChEMBL	CHEMBL76232
IUPHAR	N/A
BindingDB	26431
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
373648	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
373652	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
373646	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
373649	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
373647	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
373650	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
373657	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
373651	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
373659	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
373653	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
373661	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
373658	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
568936	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908
373654	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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