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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AL-8810
Molecular formula	C24H31FO4
IUPAC name	(Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoic acid
Molecular weight	402.506
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.7
Synonyms	5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propenyl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)- AOB5959 J-015605 Tox21_500478 (5Z,13E)-(9S,11S,15R)-9,15,DIHYDROXY-11-FLUORO-15-(2-INDANYL)-16,17,18,19,20,PENTANOR-5,13-PROSTADIENOIC ACID AL 8810 D05VOG NCGC00186007-01 AL-881011 HMS3261O18 SR-01000075674-1 A 3846 CCG-204142 LP00478 UNII-12QE8J6004 (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoic acid EU-0100046 NCGC00261163-01 246246-19-5 AL8810 HMS3648F14 SR-01000075674-4 (5Z, 13E)-(9S,11S,15R)-9,15,Dihydroxy-11-fluoro-15-(2-indanyl)-16,17,18,19,20,pentanor-5,13-prostadienoic acid AC1NSKA5 CHEMBL1332680 MolPort-027-640-944 ZINC3981322 12QE8J6004 AL-8810, >=98% (HPLC), solid GTPL1956 SR-01000075674 [ Show all ]
Inchi Key	WTYSXBKKVNOOIX-JTGCGUAKSA-N
Inchi ID	InChI=1S/C24H31FO4/c25-21-15-23(27)20(9-3-1-2-4-10-24(28)29)19(21)11-12-22(26)18-13-16-7-5-6-8-17(16)14-18/h1,3,5-8,11-12,18-23,26-27H,2,4,9-10,13-15H2,(H,28,29)/b3-1-,12-11+/t19-,20-,21+,22+,23+/m1/s1
PubChem CID	5311238
ChEMBL	N/A
IUPHAR	1956
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555205	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
555206	Prostaglandin F2-alpha receptor	P43118	Ptgfr	Rattus norvegicus (Rat)	366

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