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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Ghrp-6
Molecular formula	C46H56N12O6
IUPAC name	(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Molecular weight	873.032
Hydrogen bond acceptor	9
Hydrogen bond donor	11
XlogP	1.9
Synonyms	(S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-amino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-(1H-indol-3-yl)-propionylamino]-3-phenyl-propionylamino}-hexanoic acid amide BDBM50049479 GH-Releasing peptide His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 L-Lysinamide, L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl- Somatostatin Acetate/ GHRP-6 Acetate His-DTrp-Ala-Trp-DPhe-LysNH2 Q433 ZINC150344347 (D-Trp(2)-D-phe(5))ghrp AKOS028109152 FT-0650597 h-his-d-trp-ala-trp-d-phe-lys-nh2 KB-52247 SK&F-110679 [D-Trp7, Ala8, D-Phe10]-\|A-Melanocyte Stimulating Hormone Amide Fragment 6-11 16G840 C46H56N12O6 Ghrp, his(1)-lys(6)- His-D-Trp-Ala-Trp-D-Phe-LysNH2 MFCD00872694 UNII-4H7N4I6X6A 87616-84-0 CHEMBL105462 growth hormone releasing hexapeptide His-trp-ala-trp-phe-lysnh2 SCHEMBL9726175 [D-Trp7, Ala8, D-Phe10]-alpha-Melanocyte Stimulating Hormone Amide Fragment 6-11 (S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-amino-3-(1H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-(1H-indol-3-yl)-propionylamino]-3-phenyl-propionylamino}-hexanoic acid amide BDBM263227 GH-Releasing hexapeptide 6 His(1)-lys(6)-ghrp L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-Lysinamide Skf 110679 4H7N4I6X6A CG-042 His-DTrp-Ala-Trp-DPhe-Lys-NH2 NCGC00167341-01 US9708370, GHRP-6 ABP000559 FT-0082558 Growth hormone releasing peptide Histidyl-tryptophyl-alanyl-tryptophyl-phenylalanyl-lysinamide SK&F 110679 [D-Trp7, Ala8, D-Phe10]-alpha-Melanocyte Stimulating Hormone Amide Fragment 6-11, >=97% (HPLC) [ Show all ]
Inchi Key	WZHKXNSOCOQYQX-FUAFALNISA-N
Inchi ID	InChI=1S/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8,11-16,23-27,34,37-40,51-52H,9-10,17-22,47-48H2,1H3,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,60)(H,57,61)(H,58,64)/t27-,34-,37-,38+,39+,40-/m0/s1
PubChem CID	9919153
ChEMBL	CHEMBL105462
IUPHAR	N/A
BindingDB	50049479
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
386176	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
386177	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366

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