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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL168162
Molecular formula	C28H30N6O2
IUPAC name	(4S,9S)-N-[(1R,2R)-2-aminocyclohexyl]-24-hydroxy-3,10,14,16-tetrazahexacyclo[11.11.1.02,11.04,9.017,25.018,23]pentacosa-1(24),2,11,13,15,17(25),18,20,22-nonaene-12-carboxamide
Molecular weight	482.588
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	3.1
Synonyms	8N-[2-amino-(1R,2R)-cyclohexyl]-15-oxo-(9aS,13aS)-11,12,13,15-tetrahydro-10H-benzo[7,8]quinazolino[5,4-ab]phenazine-8-carboxamide BDBM50075918 N-[(1R)-2alpha-Aminocyclohexane-1beta-yl]-5,6-[imino(cyclohexane-1alpha,2beta-diyl)imino]-7-oxo-7H-benzo[e]perimidine-4-carboxamide
Inchi Key	WZNQIZZZHGHTTJ-YRXWBPOGSA-N
Inchi ID	InChI=1S/C28H30N6O2/c29-16-9-3-4-10-17(16)34-28(36)22-24-20-21(25-26(22)33-19-12-6-5-11-18(19)32-25)27(35)15-8-2-1-7-14(15)23(20)30-13-31-24/h1-2,7-8,13,16-19,33,35H,3-6,9-12,29H2,(H,34,36)/t16-,17-,18+,19+/m1/s1
PubChem CID	135958362
ChEMBL	CHEMBL168162
IUPHAR	N/A
BindingDB	50075918
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
569258	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
569257	Corticotropin-releasing factor receptor 2	Q60748	Crhr2	Mus musculus (Mouse)	411

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