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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL364841
Molecular formula	C28H26N2O5
IUPAC name	2-[2-methyl-1-[4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]indol-4-yl]acetic acid
Molecular weight	470.525
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.0
Synonyms	BDBM50152515 SCHEMBL991217 {2-Methyl-1-[4-(4-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-2-ylmethoxy)-benzoyl]-1H-indol-4-yl}-acetic acid
Inchi Key	XECAIYOLUPUKEJ-QFIPXVFZSA-N
Inchi ID	InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1
PubChem CID	10116114
ChEMBL	CHEMBL364841
IUPHAR	N/A
BindingDB	50152515
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
389463	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
389460	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
389461	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
389468	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
389462	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
389465	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
389464	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
389467	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
389466	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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