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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Lorcaserin
Molecular formula	C11H14ClN
IUPAC name	(5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Molecular weight	195.69
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	2.7
Synonyms	AB0148401 APD 356 Belviq GTPL2941 NCGC00182550-02 W-5409 (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine AJ-56780 AR-10A DSSTox_GSID_48659 TL80074203 202L927 AN-6779 BDBM50161646 CTK8B8482 FCH873876 LS-193332 TX-017673 (5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine 616202-92-7 AB52744 APD356 CAS-616202-92-7 DB04871 HSDB 8128 SB16626 XTTZERNUQAFMOF-QMMMGPOBSA-N 10-chloro-2-methyl-4-azabicyclo[5.4.0]undeca-8,10,12-triene AKOS006326204 AX8136671 CHEMBL360328 DSSTox_RID_82856 Lorcaserin [INN] Tox21_113018 (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine 637E494O0Z ANW-60436 Belvig D01JMC FT-0670852 NCGC00182550-01 UNII-637E494O0Z (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine AC-553 API0005054 CHEBI:65353 DSSTox_CID_28585 HY-11093 SCHEMBL169382 ZINC6733300 1H-3-Benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, (1R)- AM81248 BC224451 CS-1232 DTXSID3048659 Lorqess Tox21_113018_1 (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine [ Show all ]
Inchi Key	XTTZERNUQAFMOF-QMMMGPOBSA-N
Inchi ID	InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1
PubChem CID	11658860
ChEMBL	CHEMBL360328
IUPHAR	2941
BindingDB	50161646
DrugBank	DB04871
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
400711	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
400710	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
400712	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
400713	5-hydroxytryptamine receptor 2C	Q60F97	HTR2C	Canis lupus familiaris (Dog)	458

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