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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL288536
Molecular formula	C15H15NO2S
IUPAC name	(1S,10S)-16-thia-11-azatetracyclo[8.7.0.02,7.013,17]heptadeca-2,4,6,13(17),14-pentaene-4,5-diol
Molecular weight	273.35
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.2
Synonyms	(5aS,11bS)-4,5,5a,6,7,11b-Hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol BDBM50057837 SCHEMBL7005463 4,5,5aalpha,6,7,11bbeta-Hexahydro-1-thia-5-aza-1H-cyclopenta[c]phenanthrene-9,10-diol
Inchi Key	YWMQJPWBNVVTRC-FZMZJTMJSA-N
Inchi ID	InChI=1S/C15H15NO2S/c17-12-5-8-1-2-11-14(10(8)6-13(12)18)15-9(7-16-11)3-4-19-15/h3-6,11,14,16-18H,1-2,7H2/t11-,14-/m0/s1
PubChem CID	10540201
ChEMBL	CHEMBL288536
IUPHAR	N/A
BindingDB	50057837
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
420960	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
420957	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
420962	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
420956	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
420959	D(1) dopamine receptor	P35406		Carassius auratus (Goldfish)	363
420961	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
420958	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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