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Ligand

NameMazapertine
Molecular formulaC26H35N3O2
IUPAC namepiperidin-1-yl-[3-[[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]methyl]phenyl]methanone
Molecular weight421.585
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP4.4
Synonyms(3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone
CHEMBL10085
Piperidino[3-[[4-(2-isopropoxyphenyl)piperazino]methyl]phenyl] ketone
L001470
UNII-N0X1XW704P
[ Show all ]
Inchi KeyZKZFPRUSWCYSGT-UHFFFAOYSA-N
Inchi IDInChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3
PubChem CID60820
ChEMBLCHEMBL10085
IUPHARN/A
BindingDB50029257
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 14
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
4311015-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
4311065-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
4311005-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
4311115-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
431105Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
431112Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
431099Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
431102Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
431109D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
431104D(1B) dopamine receptorP25115Drd5Rattus norvegicus (Rat)475
431108D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
431110D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
431103D(3) dopamine receptorP19020Drd3Rattus norvegicus (Rat)446
431107D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400

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