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Ligand

NameCHEMBL8197
Molecular formulaC17H20N2O2
IUPAC name(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 1H-indole-3-carboxylate
Molecular weight284.359
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP3.8
SynonymsOprea1_462281
Tox21 110272
156-45-6
89565-68-4
AKOS022111472
[ Show all ]
Inchi KeyZNRGQMMCGHDTEI-UHFFFAOYSA-N
Inchi IDInChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3
PubChem CID5595
ChEMBLN/A
IUPHARN/A
BindingDB50007871
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 14
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
4330525-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
4330475-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
4330515-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
4330465-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
4330455-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
5572685-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
4330495-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
4330435-hydroxytryptamine receptor 4O70528HTR4Cavia porcellus (Guinea pig)388
4330445-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
5572675-hydroxytryptamine receptor 4Q62758Htr4Rattus norvegicus (Rat)406
5572695-hydroxytryptamine receptor 4P97288Htr4Mus musculus (Mouse)388
5572705-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
433048D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
433050D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

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