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Ligand

NameCHEMBL111233
Molecular formulaC23H21ClF3NO
IUPAC name4-[4-chloro-3-(trifluoromethyl)phenyl]-1-(naphthalen-2-ylmethyl)piperidin-4-ol
Molecular weight419.872
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP5.7
SynonymsBDBM50132662
4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen-2-ylmethyl-piperidin-4-ol
Inchi KeyZNWWFIQDEPGZND-UHFFFAOYSA-N
Inchi IDInChI=1S/C23H21ClF3NO/c24-21-8-7-19(14-20(21)23(25,26)27)22(29)9-11-28(12-10-22)15-16-5-6-17-3-1-2-4-18(17)13-16/h1-8,13-14,29H,9-12,15H2
PubChem CID44339463
ChEMBLCHEMBL111233
IUPHARN/A
BindingDB50132662
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
433191Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
433189Nociceptin receptorP41146OPRL1Homo sapiens (Human)370
433190Nociceptin receptorP35370Oprl1Rattus norvegicus (Rat)367

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