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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Serotonin-O-carboxymethyl-gly-tyr
Molecular formula	C23H27N5O5
IUPAC name	(2S)-2-[[2-[[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanamide
Molecular weight	453.499
Hydrogen bond acceptor	6
Hydrogen bond donor	6
XlogP	0.6
Synonyms	(S)-2-(2-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-acetylamino}-acetylamino)-3-(4-hydroxy-phenyl)-propionamide L-Tyrosinamide, N-(((3-(2-aminoethyl)-1H-indol-5-yl)oxy)acetyl)glycyl- AC1L2ZKP CHEMBL159174 133790-08-6 S-CM-Gtnh2 BDBM50286672 Serotonin-O-carboxymethyl-glycyl-tyrosinamide (2S)-2-[[2-[[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanamide DTXSID20158370 Serotonin-5-O-carboxymethyl-glycyl-tyrosinamide [ Show all ]
Inchi Key	ZRVNSPYTGPNZTB-FQEVSTJZSA-N
Inchi ID	InChI=1S/C23H27N5O5/c24-8-7-15-11-26-19-6-5-17(10-18(15)19)33-13-22(31)27-12-21(30)28-20(23(25)32)9-14-1-3-16(29)4-2-14/h1-6,10-11,20,26,29H,7-9,12-13,24H2,(H2,25,32)(H,27,31)(H,28,30)/t20-/m0/s1
PubChem CID	131670
ChEMBL	CHEMBL159174
IUPHAR	N/A
BindingDB	50286672
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
435970	5-hydroxytryptamine receptor 1D	Q60484	HTR1D	Cavia porcellus (Guinea pig)	376
435969	5-hydroxytryptamine receptor 5B	P35365	Htr5b	Rattus norvegicus (Rat)	370

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