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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL553451
Molecular formula	C38H48Cl3N5O5
IUPAC name	[(3R)-3-(3,4-dichlorophenyl)-3-[2-[4-(4-methylpiperazine-1-carbonyl)-4-pyridin-3-ylpiperidin-1-yl]ethyl]pyrrolidin-1-yl]-(3,4,5-trimethoxyphenyl)methanone;hydrochloride
Molecular weight	761.182
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	None
Synonyms	N/A
Inchi Key	ZSVRDJGQTYTNGL-JFRIYMKVSA-N
Inchi ID	InChI=1S/C38H47Cl2N5O5.ClH/c1-42-18-20-44(21-19-42)36(47)38(29-6-5-13-41-25-29)11-15-43(16-12-38)14-9-37(28-7-8-30(39)31(40)24-28)10-17-45(26-37)35(46)27-22-32(48-2)34(50-4)33(23-27)49-3;/h5-8,13,22-25H,9-12,14-21,26H2,1-4H3;1H/t37-;/m0./s1
PubChem CID	45264696
ChEMBL	CHEMBL553451
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
436678	Substance-K receptor	P30549	Tacr2	Mus musculus (Mouse)	384
436677	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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