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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL492301
Molecular formula	C21H25ClN2O3S
IUPAC name	7-[4-(2-chlorophenoxy)piperidin-1-yl]sulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Molecular weight	420.952
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50257621 7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Inchi Key	ZVFFUTQAERXNNF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H25ClN2O3S/c22-20-3-1-2-4-21(20)27-18-9-13-24(14-10-18)28(25,26)19-6-5-16-7-11-23-12-8-17(16)15-19/h1-6,15,18,23H,7-14H2
PubChem CID	44225654
ChEMBL	CHEMBL492301
IUPHAR	N/A
BindingDB	50257621
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
438322	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
438323	5-hydroxytryptamine receptor 2A	O46635	HTR2A	Canis lupus familiaris (Dog)	470
438324	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
438321	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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