#### General Statistics #### Families: 4 GPCR's: 67 Structures: 389 Species: 9 #### GPCR PDB Structures by Year #### 2000: 1 2001: 2 2002: 2 2003: 1 2004: 1 2005: 0 2006: 5 2007: 5 2008: 9 2009: 0 2010: 13 2011: 25 2012: 20 2013: 20 2014: 20 2015: 27 2016: 32 2017: 46 2018: 79 2019: 69 2020: 12 #### Distribution of Structure Resolutions #### x < 2 Å 13 2 Å <= x < 3 Å 209 3 Å <= x <= 4 Å 147 x > 4 Å 14 #### GPCR PDB Structures by Family #### Class A: 346 Class B: 22 Class C: 9 Class F: 12 #### Structures per GPCR #### 5-hydroxytryptamine receptor 1B >> 4 structure(s) >> 5V54 6G79 4IAQ 4IAR 5-hydroxytryptamine receptor 2A >> 2 structure(s) >> 6A93 6A94 5-hydroxytryptamine receptor 2B >> 8 structure(s) >> 6DRY 6DRX 4IB4 6DRZ 5TVN 6DS0 4NC3 5TUD 5-hydroxytryptamine receptor 2C >> 2 structure(s) >> 6BQH 6BQG Adenosine receptor A1 >> 3 structure(s) >> 6D9H 5UEN 5N2S Adenosine receptor A2a >> 49 structure(s) >> 3UZC 5OLG 5IUA 3REY 5WF6 3VG9 5K2D 5MZJ 5NLX 3RFM 5VRA 6PS7 5OLZ 5OLH 5UVI 5IU4 3VGA 5UIG 3UZA 5OLV 4UHR 5WF5 6GDG 5IUB 4UG2 3PWH 5OM4 6AQF 5NM2 3QAK 5MZP 5G53 5K2C 5N2R 5OLO 5K2A 4EIY 6JZH 5NM4 5IU8 5IU7 5JTB 2YDV 6GT3 6MH8 5K2B 5OM1 2YDO 3EML Apelin receptor >> 1 structure(s) >> 5VBL Beta-1 adrenergic receptor >> 24 structure(s) >> 6H7O 2YCZ 5A8E 6H7M 2VT4 6IBL 4AMJ 2Y04 4BVN 6H7J 5F8U 3ZPR 4AMI 6H7L 2Y01 2YCW 2Y03 2YCX 3ZPQ 4GPO 2Y00 6H7N 2Y02 2YCY Beta-2 adrenergic receptor >> 33 structure(s) >> 6PS0 3NY8 6PRZ 3P0G 2R4R 6E67 5D5B 3PDS 4QKX 6PS1 6NI3 4LDO 5D6L 4GBR 6PS6 6MXT 6PS5 2R4S 5D5A 3NYA 2RH1 4LDL 6PS4 3KJ6 3SN6 3NY9 5X7D 6PS2 6N48 3D4S 6PS3 5JQH 4LDE C-C chemokine receptor type 2 >> 3 structure(s) >> 5T1A 6GPX 6GPS C-C chemokine receptor type 5 >> 6 structure(s) >> 4MBS 5UIW 6AKX 6MET 6AKY 6MEO C-C chemokine receptor type 7 >> 1 structure(s) >> 6QZH C-C chemokine receptor type 9 >> 1 structure(s) >> 5LWE C-X-C chemokine receptor type 1 >> 1 structure(s) >> 2LNL C-X-C chemokine receptor type 4 >> 6 structure(s) >> 3OE0 3OE8 4RWS 3OE9 3ODU 3OE6 C5a anaphylatoxin chemotactic receptor 1 >> 3 structure(s) >> 6C1Q 5O9H 6C1R Calcitonin gene-related peptide type 1 receptor >> 1 structure(s) >> 6E3Y Calcitonin receptor >> 2 structure(s) >> 5UZ7 6NIY Cannabinoid receptor 1 >> 6 structure(s) >> 5XR8 5TGZ 6N4B 5XRA 5U09 6KQI Cannabinoid receptor 2 >> 1 structure(s) >> 5ZTY Corticotropin-releasing factor receptor 1 >> 2 structure(s) >> 4Z9G 4K5Y Cysteinyl leukotriene receptor 1 >> 2 structure(s) >> 6RZ4 6RZ5 Cysteinyl leukotriene receptor 2 >> 4 structure(s) >> 6RZ6 6RZ9 6RZ8 6RZ7 D(2) dopamine receptor >> 1 structure(s) >> 6CM4 D(3) dopamine receptor >> 1 structure(s) >> 3PBL D(4) dopamine receptor >> 3 structure(s) >> 5WIU 5WIV 6IQL Delta-type opioid receptor >> 4 structure(s) >> 4EJ4 4RWD 4N6H 4RWA Endothelin receptor type B >> 7 structure(s) >> 5GLI 6IGL 6K1Q 5GLH 5X93 5XPR 6IGK Free fatty acid receptor 1 >> 4 structure(s) >> 5KW2 5TZR 5TZY 4PHU Frizzled-4 >> 1 structure(s) >> 6BD4 G-protein coupled receptor homolog US28 >> 4 structure(s) >> 4XT3 4XT1 5WB2 5WB1 Glucagon receptor >> 5 structure(s) >> 4L6R 5XEZ 5YQZ 5XF1 5EE7 Glucagon-like peptide 1 receptor >> 8 structure(s) >> 6KK7 6KK1 6B3J 6KJV 5NX2 5VAI 5VEW 5VEX Histamine H1 receptor >> 1 structure(s) >> 3RZE Kappa-type opioid receptor >> 2 structure(s) >> 4DJH 6B73 Lysophosphatidic acid receptor 1 >> 3 structure(s) >> 4Z35 4Z34 4Z36 Melatonin receptor type 1A >> 5 structure(s) >> 6ME5 6PS8 6ME3 6ME2 6ME4 Melatonin receptor type 1B >> 4 structure(s) >> 6ME7 6ME9 6ME8 6ME6 Metabotropic glutamate receptor 1 >> 1 structure(s) >> 4OR2 Metabotropic glutamate receptor 5 >> 8 structure(s) >> 6N51 5CGC 4OO9 6N4X 6FFH 5CGD 6FFI 6N52 Mu-type opioid receptor >> 4 structure(s) >> 6DDF 5C1M 6DDE 4DKL Muscarinic acetylcholine receptor M1 >> 2 structure(s) >> 5CXV 6OIJ Muscarinic acetylcholine receptor M2 >> 9 structure(s) >> 5YC8 6OIK 4MQT 5ZK8 5ZK3 4MQS 5ZKC 3UON 5ZKB Muscarinic acetylcholine receptor M3 >> 5 structure(s) >> 4U14 5ZHP 4DAJ 4U16 4U15 Muscarinic acetylcholine receptor M4 >> 1 structure(s) >> 5DSG Muscarinic acetylcholine receptor M5 >> 1 structure(s) >> 6OL9 Neuropeptide Y receptor type 1 >> 2 structure(s) >> 5ZBQ 5ZBH Neurotensin receptor type 1 >> 11 structure(s) >> 4XEE 6OS9 5T04 6PWC 4XES 4GRV 4BUO 4BV0 4BWB 3ZEV 6OSA Nociceptin receptor >> 3 structure(s) >> 5DHH 4EA3 5DHG Orexin receptor type 1 >> 11 structure(s) >> 6TP6 6TQ7 6TP4 6TQ4 4ZJ8 6TO7 6TQ9 6TQ6 6TOD 6TP3 4ZJC Orexin receptor type 2 >> 6 structure(s) >> 6TPG 6TPN 4S0V 6TPJ 5WQC 5WS3 P2Y purinoceptor 1 >> 2 structure(s) >> 4XNV 4XNW P2Y purinoceptor 12 >> 3 structure(s) >> 4NTJ 4PXZ 4PY0 Parathyroid hormone-parathyroid hormone-related peptide receptor >> 4 structure(s) >> 6NBH 6NBF 6FJ3 6NBI Platelet-activating factor receptor >> 2 structure(s) >> 5ZKQ 5ZKP Prostaglandin D2 receptor 2 >> 2 structure(s) >> 6D26 6D27 Prostaglandin E2 receptor EP3 subtype >> 2 structure(s) >> 6AK3 6M9T Prostaglandin E2 receptor EP4 subtype >> 2 structure(s) >> 5YWY 5YHL Proteinase-activated receptor 1 >> 1 structure(s) >> 3VW7 Proteinase-activated receptor 2 >> 3 structure(s) >> 5NJ6 5NDD 5NDZ Rhodopsin >> 55 structure(s) >> 3AYN 6FK6 4BEZ 6OY9 5WKT 6FK7 2J4Y 4BEY 6FUF 4PXF 5TE3 2HPY 1JFP 5EN0 3C9M 6OFJ 3PQR 1U19 3OAX 4ZWJ 5DGY 6CMO 2I37 3DQB 1GZM 2G87 1L9H 3PXO 2I36 3AYM 2ZIY 2X72 6FKC 6FKA 3C9L 2Z73 4WW3 2I35 5W0P 2PED 6QNO 6FKD 1LN6 1HZX 4X1H 5DYS 6FK8 3CAP 6FK9 1F88 6FKB 4J4Q 6OYA 4A4M 5TE5 Smoothened homolog >> 11 structure(s) >> 5V57 4O9R 4N4W 4QIN 6OT0 5V56 5L7D 6O3C 4QIM 5L7I 4JKV Sphingosine 1-phosphate receptor 1 >> 2 structure(s) >> 3V2Y 3V2W Substance-P receptor >> 9 structure(s) >> 6HLO 6HLP 2KSA 2KS9 6J21 6HLL 6E59 6J20 2KSB Thromboxane A2 receptor >> 2 structure(s) >> 6IIV 6IIU Type-1 angiotensin II receptor >> 3 structure(s) >> 6DO1 4YAY 4ZUD Type-2 angiotensin II receptor >> 4 structure(s) >> 5XJM 5UNF 5UNH 5UNG