Detailed GPCR-I-TASSER Statistics for P59538

Submitted Sequence

>sp|P59538|T2R31_HUMAN
MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLW
VLLLNWYSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLH
LKRRVKSVILVMLLGPLLFLACQLFVINMKEIVRTKEYEGNLTWKIKLRSAVYLSDATVT
TLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCAV
YFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYW
VKGEKPSSP

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |         
Sequence MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACQLFVINMKEIVRTKEYEGNLTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCAVYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
Prediction CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCSSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCSSCCCCCCCC
Conf.Score 986899999999999999999999999999999998279887787999999999999999999999997635452156779678779999838999999999999844660899779999998466608999999999999999999713330047888850377652226899999999999999999999999999999999999860889999999818999999999999999999999999999998505771999999999998378866988418669999999999863121368799997

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |         
Sequence MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACQLFVINMKEIVRTKEYEGNLTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCAVYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
Prediction 733333331133133123313321220021001100443403201100000021100000113330000001120233300000001012212300100000010000000223110000012304310011012122323321131303221325434212123131332210111123333333233113323330220022023203433444411314002200100130221023113200200011233433211110112102101200101003143013001300220101036463668

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |         
Sec.Str
Seq		CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCSSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCSSCCCCCCCC
MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACQLFVINMKEIVRTKEYEGNLTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCAVYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
14djhA 0.14 0.19 0.89 1.46Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIR----TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSDR-----------NLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF-------------P
25tjvA 0.10 0.20 0.89 2.76Download LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILH--SRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLA----YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIF-----PHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAGKRAMSFSD--------QARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF---------------
34djhA 0.13 0.19 0.89 2.19Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRY--TKMK-TATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL----DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLL-------------RNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-------------
44ib4 0.11 0.21 0.92 1.57Download EQGNKLHWAALLILMVIIPTIGGNTLVILAVSLE---KKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEMWPLPLVLCAWLFLDVLFSTASIWHLCAISVDRYIAIK---KPIQAN-QYNSRATAFIKITVVWLIIGIAIPVPIGIETNPNNTCVLTKE-----RFGDFML--FGSLAAFFTPLAIMIVTYFLTIHALQKKAADLEDNWEQKYLQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLDNLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR----------
53odu 0.16 0.25 0.96 1.27Download NANFNKIFLPTIYSIIFLTGIVGNGLVILVMG----YQKKRSMTDKYRLHLSVADLLFVIT-LPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAIVHATNSQ----RPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSGSNIFEMLRDAYGSKGHQKRKALKTTVILILAFFACWLPYYIGISIDFILLVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSGRPLEVLFQ----
64djhA 0.13 0.19 0.90 1.65Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRY---TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL----DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSD-----------RNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-------------
74djh 0.13 0.16 0.92 1.71Download --PAIPVIITAVYSVVFVVGLVGNSLVMFVIIR---YTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIE--CSLQFPDDDWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGS---AALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF--------------
84buoA 0.16 0.20 0.91 2.38Download TDIYSKVLVTAIYLALFVVGTVGNSVTLFTLAR---KKSLQSTVDYYLGSLALSDLLILLLAMPVELYNFIWPWAFGDAGCRGYYFLRDACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPIVTATLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQ---------PGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTL---------------
94djhA 0.14 0.19 0.89 1.48Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIR----TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCPVKA-----LDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSD-----------RNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAASSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF-------------P
101l9hA 0.12 0.19 0.94 1.53Download AEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ----HKKLTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCPMSNFRF------GENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHNESFVIYMFVVHFIIPLIVIFFCYGQLVF----------TVKEAAAATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDSTTVSK
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.08 (Read more about C-score)
  • Estimated TM-score = 0.70±0.12
  • Estimated RMSD = 6.4±3.9Å

  • Download Model 2
  • C-score = -2.34

  • Download Model 3
  • C-score = -2.83

  • Download Model 4
  • C-score = -3.03

  • Download Model 5
  • C-score = -1.64


    • [Click on P59538_results.tar.bz2 to download the tarball file including all modeling results listed on this page]