Detailed GPCR-I-TASSER Statistics for Q8NGA4

Submitted Sequence

>sp|Q8NGA4|G32P1_HUMAN
MNGVSEGTRGCSDRQPGALTQGHSCSRKMNASRCLSEEVGSLRPLTMAVLSASFVVGVLG
NGLVPWVTVFRMARTVSTVCFFHLALADFMLSLSLPILVYYIVSRQWLLGEWACKLYTGF
VFLTFSTSNCLLVLISVDRCISVLYPVWALNHRTEQRASWLAFGVWLLAAALCSAHLKFR
TTRKWNGCMQCYLQFNLENETAQMWTQEVFGRQMAVIMAHFLLGFLGPLAIIGTCAHLIR
AKLLREGWVHANRPKRLLLVLVSALSAGSHLT

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |            
Sequence MNGVSEGTRGCSDRQPGALTQGHSCSRKMNASRCLSEEVGSLRPLTMAVLSASFVVGVLGNGLVPWVTVFRMARTVSTVCFFHLALADFMLSLSLPILVYYIVSRQWLLGEWACKLYTGFVFLTFSTSNCLLVLISVDRCISVLYPVWALNHRTEQRASWLAFGVWLLAAALCSAHLKFRTTRKWNGCMQCYLQFNLENETAQMWTQEVFGRQMAVIMAHFLLGFLGPLAIIGTCAHLIRAKLLREGWVHANRPKRLLLVLVSALSAGSHLT
Prediction CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCSSSSSCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHSSSSSSSSSCCCCCC
Conf.Score 99887788888888988877888878777767666655422576699999999999988789844635530667589999999999999999989999999825999884089999999999999999999999999989999845343015663322132799999999998489886512624992589613787554310011146889999999999999999999999999999999974577666623563167899997174278

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |            
Sequence MNGVSEGTRGCSDRQPGALTQGHSCSRKMNASRCLSEEVGSLRPLTMAVLSASFVVGVLGNGLVPWVTVFRMARTVSTVCFFHLALADFMLSLSLPILVYYIVSRQWLLGEWACKLYTGFVFLTFSTSNCLLVLISVDRCISVLYPVWALNHRTEQRASWLAFGVWLLAAALCSAHLKFRTTRKWNGCMQCYLQFNLENETAQMWTQEVFGRQMAVIMAHFLLGFLGPLAIIGTCAHLIRAKLLREGWVHANRPKRLLLVLVSALSAGSHLT
Prediction 66543443532444434433444323344344414464242010000221120023123312200000002333100000000001001200000111001104430110200022011113211111010000003100100010030242233320200001002100100101000120344732220103033644344324432322310111221130233122101301120021024364553310000000000002002317

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit
Iden1Iden2Cov.Norm.
Z-score
Download
Align.
                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |            
Sec.Str
Seq
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCSSSSSCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHSSSSSSSSSCCCCCC
MNGVSEGTRGCSDRQPGALTQGHSCSRKMNASRCLSEEVGSLRPLTMAVLSASFVVGVLGNGLVPWVTVFRMARTVSTVCFFHLALADFMLSLSLPILVYYIVSRQWLLGEWACKLYTGFVFLTFSTSNCLLVLISVDRCISVLYPVWALNHRTEQRASWLAFGVWLLAAALCSAHLKFRTTRKWNGCMQCYLQFNLENETAQMWTQEVFGRQMAVIMAHFLLGFLGPLAIIGTCAHLIRAKLLREGWVHANRPKRLLLVLVSALSAGSHLT
14n6hA 0.27 0.28 0.96 2.56Download LANEGKVKEAQAAAEQLKTTRNAYIQKYLGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSP----------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSLRRITRMVLVVVGAFVVPIHIF
24mbsA 0.23 0.25 0.83 3.36Download ----------------------------------KINVKQIAARLLPPLYSLVFIFGFVGNMLVILILIYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAA-AQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFPYSQ---------YQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLREEEKKRHRDVRLIFTIMIVYWAPYNI-
34n6hA 0.30 0.27 0.85 3.32Download ------------------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPS----------WYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSLRRITRMVLVVVGAFVVCIHIF
44xnv 0.26 0.26 0.85 1.47Download ------------------------------SFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYP-KSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKKTITCYDTTSDE----------YLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKMKPLRRKSIYLVIIVL-TVFAVSYIP
54xnv 0.26 0.26 0.85 1.16Download ------------------------------SFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHKPWSGISVYMFNLALADFLYVLTLPALIFYYFKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYP-KSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRNKTITCYDTTSDEY----------LRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKMKKLRRKSIYLVIIVLTVFYIPFHVM
65x33A 0.27 0.25 0.81 2.87Download ---------------------------------------TFIPLLAMILLSVSMVVGLPGNTFVVWSILKRMRRSVTALMVLNLALADLAVLLTAPFFLHFLTWGTWSFGLAGCRLCHYICGVSMYASVLLITAMSLDRSLAVASPFLSQKVRTKTAARWLLVGIWGASFLLATPVLAFRKVVKLTETDLCLAVYPS------------DRHKAFHLLFEAFTGFVVPFLIVVASYADISRRLRARG--RRRRTGRLVVIIILAFWLPYHVV
74xnv 0.29 0.26 0.73 1.69Download ---------------------------------------GFQFYYLPAVYILVFIIGFLGNSVAIWMFVFMKPWSGISVYMFNLALADFLYVLTLPALIFYYNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYP-KSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRNKTITCYDTTSDE----------YLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKMK------------------------
84djhA 0.28 0.26 0.76 3.18Download -----------------------------------SP---AIPVIITAVYSVVFVVGLVGNSLVMFVIIRYKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDD---------YSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGN-------------------I
95x33A 0.27 0.25 0.81 2.95Download -------------------------------------SNTFIPLLAMILLSVSMVVGLPGNTFVVWSILKRMKRSVTALMVLNLALADLAVLLTAPFFLHFLTWGTWSFGLAGCRLCHYICGVSMYASVLLITAMSLDRSLAVASPFLSQKVRTKTAARWLLVGIWGASFLLATPVLAFRKVVKLNETDLCLAVYPS------------DRHKAFHLLFEAFTGFVVPFLIVVASYADISRRLRARG--RRRRTGRLVVIIILAFWLPYHVV
104n6hA 0.27 0.28 0.96 4.03Download LANEGKVKEAQAAAEQLKTTRNAYIQKYLGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSP----------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGRRITRMVLVVVGAFWAPIHIF
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.32 (Read more about C-score)
  • Estimated TM-score = 0.76±0.10
  • Estimated RMSD = 5.3±3.4Å

  • Download Model 2
  • C-score = -1.05

  • Download Model 3
  • C-score = -0.46

  • Download Model 4
  • C-score = -0.25

  • Download Model 5
  • C-score = -6.01


  • [Click on Q8NGA4_results.tar.bz2 to download the tarball file including all modeling results listed on this page]