GO:0003824	F	0.59	catalytic activity
GO:0097159	F	0.45	organic cyclic compound binding
GO:1901363	F	0.44	heterocyclic compound binding
GO:0016740	F	0.43	transferase activity
GO:0003676	F	0.37	nucleic acid binding
GO:0004842	F	0.34	ubiquitin-protein transferase activity
GO:0019899	F	0.31	enzyme binding
GO:0022891	F	0.26	substrate-specific transmembrane transporter activity
GO:0031625	F	0.24	ubiquitin protein ligase binding
GO:0015075	F	0.24	ion transmembrane transporter activity
GO:0008324	F	0.22	cation transmembrane transporter activity
GO:0003677	F	0.20	DNA binding
GO:0046873	F	0.19	metal ion transmembrane transporter activity
GO:0016787	F	0.18	hydrolase activity
GO:0003723	F	0.17	RNA binding
GO:0008092	F	0.16	cytoskeletal protein binding
GO:0005261	F	0.16	cation channel activity
GO:0046872	F	0.14	metal ion binding
GO:0072509	F	0.11	divalent inorganic cation transmembrane transporter activity
GO:0005198	F	0.11	structural molecule activity
