GO:0099600	F	0.93	transmembrane receptor activity
GO:0022891	F	0.79	substrate-specific transmembrane transporter activity
GO:0015075	F	0.78	ion transmembrane transporter activity
GO:0005216	F	0.77	ion channel activity
GO:0004871	F	0.77	signal transducer activity
GO:0004888	F	0.76	transmembrane signaling receptor activity
GO:0022836	F	0.58	gated channel activity
GO:0005254	F	0.55	chloride channel activity
GO:0015276	F	0.54	ligand-gated ion channel activity
GO:0005230	F	0.52	extracellular ligand-gated ion channel activity
GO:0005231	F	0.50	excitatory extracellular ligand-gated ion channel activity
GO:0043167	F	0.45	ion binding
GO:0016917	F	0.43	GABA receptor activity
GO:0004890	F	0.42	GABA-A receptor activity
GO:0030594	F	0.35	neurotransmitter receptor activity
GO:0043169	F	0.32	cation binding
GO:0008324	F	0.32	cation transmembrane transporter activity
GO:0015464	F	0.31	acetylcholine receptor activity
GO:0005261	F	0.31	cation channel activity
GO:0004889	F	0.30	acetylcholine-activated cation-selective channel activity
GO:0042166	F	0.29	acetylcholine binding
GO:0043168	F	0.16	anion binding
GO:0031406	F	0.14	carboxylic acid binding
GO:0016594	F	0.13	glycine binding
GO:0004930	F	0.13	G-protein coupled receptor activity
GO:0016933	F	0.11	extracellular-glycine-gated ion channel activity
GO:0005237	F	0.11	inhibitory extracellular ligand-gated ion channel activity
