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# D-I-TASSER results for O43861-D1

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Input Sequence in FASTA format

>O43861 (1147 residues) MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEE GFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWL GCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIV EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYII PISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIF KRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR IHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTES VGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD VAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS HLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ CPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS LAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL YQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLIS IYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCY VSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPP SYCKLAS

Predicted Secondary Structure

Sequence

20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 1120 1140
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Prediction
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCSSSCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCSSSSSSSSCCCCCSSSSCCCCSSCCSSSSSSSCCCCCCSSSSCCCCCCCCCCSSCCCCHHHHCCCCHHHHHHCSSSSSSCCCCCCCCSSSSSSSSCCCCCCCCCCCCCCH S H SCCSSSSCCSSSSSSSSSCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHH S HHHHHHHHHHHHHHHHCCCCCCSSCCCCHHHHHCCSSSSSCCCCCCCCCCCSSSSSSSSCCSSSCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCSSSCCCCCCHHHHHHHHHHHCCSSSSCCCCSSSSSSCCCCSSSSSSSSSSCCCCCCCCSSSSSSCCCCCSSSSSSCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCSSSSSSSSCCHHHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHCCCSSSSSSSSSCCCCCCHHHHHHHHHHHCCSSSSSCCCCHHHHHHHHHHCCCCCCCCSSSSSSCCCCHHHHHHHHHHHHCCCCCSSSSCHHHHHHHHHHHHHHHHHHHHCCCCSSSSCCCHHHHHHHHHHHHHHCCCSSSSSCCCCCCHHHHHHCHHCCCCCCCCHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH SCCCCHHHHCC
Confidence
H:Helix; S:Strand; C:Coil
Predicted Solvent Accessibility

Sequence | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 1120 1140 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Prediction |
| Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Contact, Hydrogen and Distance Map Used in D-I-TASSER simulation

Contact Map | Distance Map | Hydrogen bond networks

D-I-TASSER simulation is guided by the consensus contact map (left figure), distance map (middle figure) and Hydrogen bond network (right figure) derived based on confidence scores of DeepPotential. In the contact, distance map and hydrogen bond networks, the axes mark the residue index along the sequence. For the contact map, each dot represents a residue pair with predicted contact, while for the distance map and hydrogen bond network, a color scale represents a distance of 1-20+ angstroms or a angle of 0-180 degree.

Top 10 threading templates used by D-I-TASSER

Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Downloadalignment |  | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 1120 1140 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SS Seq | CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCSSSCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCSSSSSSSSCCCCCSSSSCCCCSSCCSSSSSSSCCCCCCSSSSCCCCCCCCCCSSCCCCHHHHCCCCHHHHHHCSSSSSSCCCCCCCCSSSSSSSSCCCCCCCCCCCCCCH S H SCCSSSSCCSSSSSSSSSCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHH S HHHHHHHHHHHHHHHHCCCCCCSSCCCCHHHHHCCSSSSSCCCCCCCCCCCSSSSSSSSCCSSSCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCSSSCCCCCCHHHHHHHHHHHCCSSSSCCCCSSSSSSCCCCSSSSSSSSSSCCCCCCCCSSSSSSCCCCCSSSSSSCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCSSSSSSSSCCHHHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHCCCSSSSSSSSSCCCCCCHHHHHHHHHHHCCSSSSSCCCCHHHHHHHHHHCCCCCCCCSSSSSSCCCCHHHHHHHHHHHHCCCCCSSSSCHHHHHHHHHHHHHHHHHHHHCCCCSSSSCCCHHHHHHHHHHHHHHCCCSSSSSCCCCCCHHHHHHCHHCCCCCCCCHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH SCCCCHHHHCC
1 | 6lcpA | 0.22 | 0.17 | 5.48 | 1.17 | DEthreader |  | -----------------------------------------------------------------------------------------------------------------------------YFNLPPQQFPRNKIRTAKYTFIKNLWFQ FHNIANIFF LFLVILVIFPIFGGVNPGLNSVP LIVIITV TAIKDA IEDYR RTILDIELNNAPVHRLKARFHKDAWKNLVVGDFVRIYNDDELPADIIILATSDPD-GACYVETKNL D-G-ETNL K VRQ-AL-RCG-RTLKHARDCAFVIESEPQNLYKYNGAIRWKEPREMSE-PIGIDNLLLRGCHLRNTEWALGVVVFTHDTKIMM NAGITPSKRARIARE L NFNVICNFGILLIMCLIAAIANGIAWTGFITFWAAVIVFQNLVP I S LYISLEIVRTLQAFFIYSDVGMYPCIPKSWNISDDVGQIEYIFSD K T G T L T Q NVMEF KKATINGQPY GEKAILMTFIAPDF--EDLAG----P--E----QQQATEHFMLA--LA-LCH-TVV----------AE-KQPGDP--------P-------KMIFK--AQSPDEAALVATAR-------------LGMSDGGI-------------------------VLSIIEFNSSRKRMKGADSVIYSRLTAHLEMFAVE G L R T LCIA-RREHDLAATAL-EN-----------------REEKL EEVADIEGGTAIE DRL QDGVPDTIALLADA G I KLWVL T G D KVE T AINIGFSCNLLNNDMDLLRLQVNESDLEQLKTNLERFNMSPYA L V IDGFTLRWVLSDLKQKFLLLCKQ CKSVLC C RVS PAQ K AAVVSMVKNGLDVMTLSI G D GAN D VAM I QEA DVGVG IAGEE GRQ AVMSSD FAIGQ F RFLQR LVLV H G RWS YRRLAETISNFFYKNMIWTWSIFWYQCYCNFDIAYIFEYTYILMFNLFFTSVP VILMGVLDQDSDTVSLAVPQL YRRGIERKEWTQTKFWLYMIDGVY QSVMSFFIPFIVVVS ERTRLGAYIAHPAVITINGYILINTYRWDW L MLLSIVL SDVFIFFWTGVYTATTYSA------GFYQAAPQVYQELTFWMCLIVTPALCLLPRLVVKCIQFPYDVDIIRE
2 | 6lcpA | 0.20 | 0.17 | 5.35 | 1.55 | EigenThreader |  | ----------------------------------APRKLYFNLPPELKDEEGHPIQQFPRNKIRTAKYTPLSFIPKNLWFQFHNIANIFFLFLVILV---------------------------IFPIFGGVNP----------------------------------------GLNSVPLIVIITVTAIKDAIEDYRRTILDIELNN------APVHRLSGKARKDAWKNLVV G DFVRIYNDDELPADIIILAT SDPDGACYVETKNL D G E TNLKVRQALRCGRTLKHA-------------RDCERAQFVIESAIRWKEPREMSEPIGIDNLLLRGCHLRTEWALG V VVFT GH-------DTKIMMNAGINFNVICNFGILLIMCLIAAIANGIAWGKTDASLAWFEALTGFITFWAAVIVFLYISLEIVRTLQAFFIYSDVGMYYEKISWNISDDVGQIEYIFSD K T G T-----LEF KKATINGQPY GEAYTEIAAAKV RAIRGLRELHDNPYLHDEDM-----TFIALAGKNGPEQQQATEHFMLAL--------ALCHTVVAEKQ----PGDPPKMI-FKAQS P D EAA L VATARDMGFTVLGMGGINVNVM----GKDMHFPVLSIIEFNSRK R MSTI V RMPDGRILLFCKGA----DSVIYSRLRETAQHLEMFAVE G L R T LCIAERELSE EEYREWRREHDLAATALENREEKLEEVA-----DKIGTAIEDRLQ---DGVPDTIALLADA G I KLWVL T G D KVE T AINIGFSCNLLNNDM-DLLRLQ VNESDAEQLKTNLERFNMTGA L V IDGFTLRWVLSDSLKQKFLLLCKQCKSVLCCVS PAQ K AAVVSMVKNGLDVMTLSI G D GAN D VAM I QEA DVGVG IAVMSS-------D FAIGQ F RFLQR LVLV H G RWS YRRLAETISNFFYKNMIWTWSIFWYQCYFNLFFTSVPVILMGVL---------------D Q D VSDTVSLAVPQL YRRGIERKEWTKFWLYMIDGVYQSVMSFFIPFIFVVLVS ERTRLGAYIAHPAVITINGYILINTYRWDW L MLLSIVL SDVFIFFWTGVYT---ATTYSAGFYQAAPQVYQELT FWMCLIVTPALCLL PRLVVKCIQKQRFPYDVDIIRE
3 | 7ky5A | 0.27 | 0.24 | 7.27 | 4.71 | SPARKS-K |  | -------------------------------------------------------------------------------------------------------------NRSDELR T VYYNLPLPPLAVYP R NKIRTTK YTPLT FFPKNILFQ FHNFANIY F LILLILGAFQIFGVTNPGFASVP LIVIVIITAIKDGIEDSR RTVLDLE V NNTRTHILSGCRFAKDYWKNVKV G DIVRVHNNDEI PAD MILLST SDVDGACYVETKNL D G E TNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNWQDTQNGNIRNEPVNINNLLLRGCTLRNTWAMGMV IFT GDDTKIMINAGVTPTKKSRISRE L NFSVILNFVLLFILCFTAGIVNGVYYNGFVSFWVAVILYQSLVP I S LYISVEIIKTAQAIFIYTDVLLYPCTPKSWNISDDL GQIEYIFSD K T G T L T Q NVMEF KKCTINGV S Y GRAYEKEEIAKDRETMIDELRSMSDNTQFCPSKEIVEDLKGSSGDHQQKCCEHFLLALAL C HSVLVEPNKD----------------DPKKLDIKAQS P D ESA L VSTARQLGYSFVGSSKSGLIVEIQ-GVQKEFQVLNVLEFNSSRK R MSCIIKIPGEPKALLICK G A DSVIYSRLTLLEKTALHLEEYATE G L R T LCLAQREL TWSEYERWVKTYDVAAASVTNREEELDKVTDVIE R ELIL LGGTAIE DRL QDGVPDSIALLAEA G I KLWVL T G D KVE T AINIGFSCNVLNNDMELLVVKASGPIQVVNNLVTKYLREGNFAVIIDG DALKVALNGMRRKFLLLCKNCKA VLC C RVS PAQ K AAVVKLVKKTLDVMTLA I G D GSN D VAM I QSA DVGVG IAGEE GRQ AVMCSDYAIGQ F RYVTR LVLV H GKWCY K RLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVP VILLAVD Q D VSDTVSM LVPQL YRVGILRKEWNQTKF LWYMLDGVY QSVICFFFPYLAYHDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICL S LAVFYGWTGIWTS---SSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLL PRFTIDCIRKIFYPKDIEIVRE
4 | 6lcpA | 0.27 | 0.23 | 7.16 | 2.00 | MapAlign |  | -----------------------------------------------------------------------------------------------------------------APRKLYFNEEGHPIQQFP R NKIRTAK YTPLSF I PKNLWFQ FHNIANIFF LFLVILVIFPIFGGVNPGLNSVP LIVIITV TAIKDA IEDYR RTILDIELNN-APVHRLSARFHKDAWKNLVV G DFVRIYNDDELPADIIILAT SDPDGACYVETKNL D G E TNLKVRQALRCGRTLKHARDCERAQFVIESEPP QPNLYKYNGAIRWK-EPREMSEPIGIDNLLLRGCHLRNTWALG V VVFT GHDTKIMM NAGITPSKRARIARE L NFNVICNFGILLIMCLIAAIANGIAWPALTGFITFWAAVQNLVP I S LYISLEIVRTLQAFFIYSDVGMYYCIPKSWNISDDVGQIEYIFSD K T G T L T Q NVMEF KKATINGQPY G AEEIAAAKVRAIRGLRELNPYLHDEDMTFIAPDFVEDLAGKNGPEQQQATEHFMLALAL C HTVVAEKQ-----------------PGDPPKMIFKAQP D EAA L VATARDMGFTVLGMSDGGINVNVM-GKDMHFPVLSIIEFNSSRK R MSTI V RMP-DGRILLFCK G A DSVIYSRLKMRRETAQHLEMFAVE G L R T LCIAERELSE EEYREWRREHDLAATALENREEKLEEVADKIE RDLTL LGGTAIE DRL QDGVPDTIALLADA G I KLWVL T G D KVE T AINIGFSCNLLNNDMDLLRLQVNEYLQLAEEQLKTNLPSPTYA L V IDGFTLRWVLSSLKQKFLLLCKQ CKSVLC C RVS PAQ K AAVVSMVKNGLDVMTLSI G D GAN D VAM I QEA DVGVG IAGEE GRQ AVMSSD FAIGQ F RFLQR LVLV H G RWS YRRLAETISNFFYKNMIWTWSIFWYQCYCNFDIAYI-FEYTYILMFNFFTSVP VILMGVD Q D VSDTVSLAVPQL YRRGIERKEWFWLYMIDGVYQSVMSFFIPFIFVVGLDVS ERTRLGAYIAHPAVITINGYILINTYRWDW L MLLSIVL SDVFIFFWTGVYTATTYSAGF---YQAAPQVYQELT FWMCLIVTPALCLL PRLVVKCIQKQRFPYDVDII--
5 | 6lcpA | 0.25 | 0.23 | 7.00 | 0.79 | CEthreader |  | ----------------------------------------------------------------------------------------------------------APR KLYFNLPPELKDEEGHPIQQFP R NKIRTAK YTPLSF I PKNLWFQ FHNIANIFF LFLVILVIFPIFGGVNPGLNSVP LIVIITV TAIKDA IEDYR RTILDIELNNAPVHRLSGKARHKDAWKNLVV G DFVRIYNDDELPADIIILAT SDPDGACYVETKNL D G E TNLKVRQALRCGRTLKHARDCERAQFVIESEPP QPNLYKYNGAIRWKEPREMSE-PIGIDNLLLRGCHLRNTWALG V VVFT GHDTKIMM NAGITPSKRARIARE L NFNVICNFGILLIMCLIAAIANGIALTGFITFWAAVIVFQNLVP I S LYISLEIVRTLQAFFIYSDVGMYPCIPKSWNISDDVGQIEYIFSD K T G T L T Q NVMEF KKATINGQPY GEAYTEAQAGMDRRGINVEEEAKVIREEIAAAKVRAIRGLRELHDNIAPDFVEDLAGKNGPEQQQATEHFMLALALCHTVVAEKQPGDPPKMIFKAQS P D EAA L VATARDMGFTVLGMSDGGINVNVMGKDMHF-PVLSIIEFNSSRK R MSTI V RM-PDGRILLFCK G A DSVIYSRLDMRRETAQHLEMFAVE G L R T LCIAERELSE EEYREWRREHDLAATALENREEKLEEVADKIE RDLTL LGGTAIE DRL QDGVPDTIALLADA G I KLWVL T G D KVE T AINIGFSCNLLNNDMDLLRLQVNEYLQLAEEQLKTNLERPTYA L V IDGFTLRWVLSSLKQKFLLLCKQ CKSVLC C RVS PAQ K AAVVSMVKNGLDVMTLSI G D GAN D VAM I QEA DVGVG IAGEE GRQ AVMSSD FAIGQ F RFLQR LVLV H G RWS YRRLAETISNFFYKNMIWTWSIFWYQCYCNFDIAYIFEYTYILMFNLFFTSVP VILMGVLQ D VSDTVSLAVPQL YRRGIERKEWTQTKFWLYMIDGVY QSVMSFFIPFIFVVLERTRLGAYIAHPAVITINGYILINTYRWDW L MLLSIVL SDVFIFFWTGVYTATTYSAG---FYQAAPQVYQELT FWMCLIVTPALCLL PRLVVKCIQKQRFPYDVDIIRE
6 | 6rohA | 0.30 | 0.26 | 7.82 | 3.78 | MUSTER |  | ------------------------------------------------------------------------------------------------------------------PRVIHINDSANSSFGYSDNHISTTK Y NFAT FLPKFLFQEFSKYAN LFF LCTSAIQQV PHVSPTNRY TTIGTLLVV LIVSAMKECIEDIKRANSD K ELNNSTAEIFSEDDFVEKRWID IRV G DIIRVKSEEPI PADTIILSSS EPEGLCYIETANL D G E TNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYE G TMTLNDR----QIPL SPDQMILRGALRNTAWIFGLV IFT GHE TKLLRNATATPIKRTAVEKIIN RQIIA L FTVLIVLILISSIGNVIMSLFFKDFLTFWIL F SNLVP I S LFVTVELIKYYQAFMIGSDLDLYPT V V R T SSLVE E L GQIEYIFS-K T G T L TRNIMEF KSCSIAGHCYIDKIPE----------DKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIINDFLTLLATC HTVIPEFQS------------------DGSIKY Q AAS P D EGA L V QGGADLGYKFIIRKPNSVTVLLETGEEKEYQLLNICEFNSTRK R MSAIFRFPD-GSIKLFCK G A DTVILERLDDVEATMRHLEDYASE G L R T LCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIE DKL QDGVPETIHTLQEA G I K I WVL T G DRQE T AINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNTLA L V IDGKS LGFALEELEDYLLTVAKLCKA VIC C RVS PLQ K ALVVKMVKRKSSSLLLA I G D GAN D V S M I Q A AHVGVG ISGME GMQ AARSA DIAVGQ FKFLKKL LLV H GSWS YQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVD QFVSSRLLERY PQL Y KLGQK GQFFSVYIFWGWIINGFFHSAIVFIGTILIYLADHWSWGVTVYTTSVIIVLGKAA LVTNQWTKFTLIAIPGS LLFWLIFFPIYASIFPHANISREYYVVKHTYGSGVFWLTLIVLPIFALVRDFLWK YYKRMYEPETYHVQQF
7 | 7ky5A | 0.27 | 0.24 | 7.36 | 3.51 | HHsearch |  | -------------------------------------------------------------------------------------------------------------NRSDELR T VYYNLPLLPLAVYP R NKIRTTK YTPLT FFPKNILFQ FHNFANIY F LILLILGAFQIFGVTNPGFASVP LIVIVIITAIKDGIEDSR RTVLDLE V NNTRTHILSGCRFAKDYWKNVKV G DIVRVHNNDEI PAD MILLST SDVDGACYVETKNL D G E TNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNIRNEPVNINNLLLRGCTLRNTKAMGMV IFT GDDTKIMINAGVTPTKKSRISRE L NFSVILNFVLLFILCFTAGIVNGVYTNGFVSFWVAVILYQSLVP I S LYISVEIIKTAQAIFIYTDVLLYPCTPKSWNISDDL GQIEYIFSD K T G T L T Q NVMEF KKCTINGV S Y GRAYTEALAGLRVEGRREKEEISMSDN TQFCPEDLTEDLKGSSGDHQQKCCEHFLLALAL C HSVLVEPNKDD----------------PKKLDIKAQS P D ESA L VSTARQLGYSFVGSSKSGLIVEIQ-GVQKEFQVLNVLEFNSSRK R MSCIIKIPGEPKALLICK G A DSVIYSRLDRLEKTALHLEEYATE G L R T LCLAQREL TWSEYERWVKTYDVAAASVTNREEELDKVTDVIE R ELIL LGGTAIE DRL QDGVPDSIALLAEA G I KLWVL T G D KVE T AINIGFSCNVLNNDMELLVVKASGEDVEEFEE LKEGLPQGNFAVIIDG DALKVALNEMRRKFLLLCKNCKA VLC C RVS PAQ K AAVVKLVKKT-LDVMTLI G D GSN D VAM I QSA DVGVG IAGEE GRQ AVMCSDYAIGQ F RYVTR LVLV H GKWCY K RLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVP VILL V L D Q D VSDTVSM LVPQL YRVGILRKEWNQTKF LWYMLDGVY QSVICFFFPYLAYHKHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICL S LAVFYGWTGIWTSSSSS-NEFYKG--AARVFAQPAYWAVLFVGVLFCLL PRFTIDCIRKIFYPKDIEIVRE
8 | 7ky5A | 0.26 | 0.23 | 7.22 | 7.48 | FFAS-3D |  | -------------------------------------------------------------------------------------------------------------NRSDELR T VYYNLPGLPLAVYP R NKIRTTK YTPLT FFPKNILFQ FHNFANIY F LILLILGAFQIFGVTNPGFASVP LIVIVIITAIKDGIEDSR RTVLDLE V NNTRTHPNPECRFAKDYWKNVKV G DIVRVHNNDEI PAD MILLST SDVDGACYVETKNL D G E TNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIPVNINNLLLRGCTLRNTKWAMGMV IFT GDDTKIMINAGVTPTKKSRISRE L NFSVILNFVLLFILCFTAGIVNGVYYNGFVSFWVAVILYQSLVP I S LYISVEIIKTAQAIFIYNAKLDYPCTPKSWNISDDL GQIEYIFSD K T G T L T Q NVMEF KKCTINGV S Y GRAYKEE IAKDRETMIDELRSMSDNTQFCPEDKEIVEDLKGSSGDHQQKCCEHFLLALAL C HSVLV----------------EPNKDDPKKLDIKAQS P D ESA L VSTARQLGYSFVGSSKSGLIVEIQ-GVQKEFQVLNVLEFNSSRK R MSCIIKIPGEPKALLICK G A DSVIYSRLDRLEKTALHLEEYATE G L R T LCLAQREL TWSEYERWVKTYDVAAASVTNREEELDKVTDVIE R ELIL LGGTAIE DRL QDGVPDSIALLAEA G I KLWVL T G D KVE T AINIGFSCNVLNNDMELLVVKASGGSDPIQVVNNLVTPQGNFAVIIDG DALKVALEEMRRKFLLLCKNCKA VLC C RVS PAQ K AAVVKLVKKTLDVMTLA I G D GSN D VAM I QSA DVGVG IAGEE GRQ AVMCSDYAIGQ F RYVTR LVLV H GKWCY K RLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVP VILLAVD Q D VSDTVSM LVPQL YRVGILRKEWNQTKF LWYMLDGVY QSVICFFFPYLAYHKNRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICL S LAVFYGWTGIWT---SSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLL PRFTIDCIRKIFYPKDIEIVR-
9 | 6rohA | 0.23 | 0.18 | 5.74 | 1.60 | EigenThreader |  | -------------------------------------------------------------------------------------------------------------------PRIHINDSLANSSFGYSDNHISTTKYNLPKFLFQEFS---KYAN LFF LCTSAIQQV PHVSPTNRY TTIGTLLVV LIVSAMKECIEDIKRANSD K ELNNSTAEIFSEAHFVEKRWID IRV G DIIRV-KSEEPIPADTIILSS EPEGLCYIETANL D G E T-NLKIKQSR--VETAKF-------IKVVSEQPNSSLYTYE G TMTLN---DRQIPLSPD-QMILRGATLNTAWIFGLV IFT GN-------ATATPIKRTAVEKIIN RQIIA L FTVLIVLILISSIG------NVIMSTADLFFKDFLTFWILFVTVELIKYYQAFMIGSDLDLYYEKTDTPTSLVEELGQIEYIFSK T G T-----LEF KSCSIAGHIDKIPED----------------KTATVEDGIEV----GYRKFNDPSDE--DSPIINDFLTLLATCH--------TVIPEFQ------SDGSIK-Y Q AAS P D EGA L V QGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPDGSLFCKGA-----DTVILERLDEATMRHLEDYASEGLRTLCLAMRDIE EWNSIYNEAATDEAANLIEK-------------NLILIGATAIE DDG---VPETIHTLQEA G I K I WVL T G DRQE T AINIGMSCRLLSEDM-NLLIINEETRDDNLL EKINALNEHQLA L V IDGKS LGFA----LDYLLTVAKLCKA VIC C RVS PLQ K ALVVKMVKRKSSSLLLA I G D GAN D V S M I Q A AHVGVG ISGME GMQ AARSA DIAVGQ FKFLKKL LLV H GSWS YQRISVAILYSFYKNTALYMTQFWYVFAMESWTMSFYNLF----------FPPFVIGVFD QFVSSRLLERY PQL Y KLGQK GQFFSVYIFWGWIINGFFHSAIVFIGTILIYRLADHWSWGVTVYTTSVIIVLGKAALVTNQSLLFWLIFFPIYAPHAN----------ISREYYGVVKHTYG--SGVFWLTLPIFALVRDFLWKYYKRMYEPETYHVQQFQNA
10 | 6rohA | 0.30 | 0.26 | 7.81 | 5.18 | CNFpred |  | -------------------------------------------------------------------------------------------------------------------RVIHINDSLANSFGYSDNHISTTK Y NFAT FLPKFLFQEFSKYAN LFF LCTSAIQQV PHVSPTNRY TTIGTLLVV LIVSAMKECIEDIKRANSD K ELNNSTAEIFSEDDFVEKRWID IRV G DIIRVKSEEPI PADTIILSSS EPEGLCYIETANL D G E TNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYE G TMTLND----RQIPL SPDQMILRGATLRNTWIFGLV IFT GHE TKLLRNATATPIKRTAVEKIIN RQIIA L FTVLIVLILISSIGNV-AGLFFKDFLTFWIL F SNLVP I S LFVTVELIKYYQAFMIGSDLDLYPT V V R T SSLVE E L GQIEYIFSMK T G T L TRNIMEF KSCSIAGHCYIDKIPEDKTATVEDGIEVGY----------RKFDDLKKKLNDPSDEDSPIINDFLTLLATC HTVIPEFQS------------------DGSIKY Q AAS P D EGA L V QGGADLGYKFIIRKPNSVTVLLEEGEEKEYQLLNICEFNSTRK R MSAIFRFP-DGSIKLFCK G A DTVILERLDYVEATMRHLEDYASE G L R T LCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIE DKL QDGVPETIHTLQEA G I K I WVL T G DRQE T AINIGMSCRLLSEDMNLLIINEE-TRDDTERNLLEKIN-NTLA L V IDGKS LGFALEELEDYLLTVAKLCKA VIC C RVS PLQ K ALVVKMVKRKSSSLLLA I G D GAN D V S M I Q A AHVGVG ISGME GMQ AARSA DIAVGQ FKFLKKL LLV H GSWS YQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDFVSSRLLERY PQL Y KLGQK GQFFSVYIFWGWIINGFFHSAIVFIGTILIY-ADHWSWGVTVYTTSVIIVLGKAA LVTNQWTKFTLIAIPGS LLFWLIFFPIYASIFPHANISREYYGVVKHTGSGVFWLTLIVLPIFALVRDFLWK YYKRMYEPE-------
(a) | ID1 is the number of template residues identical to query divided by number of aligned residues.
(b) | ID2 is the number of template residues identical to query divided by query sequence length.
(c) | Cov is equal the number of aligned template residues divided by query sequence length.
(d) | Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment and is highlighted in bold.
(e) | Download alignment lists the threading program used to identify the template, and provide the 3D structure of aligned regions of threading templates (threading[1-10].pdb.gz).
(f) | Template residues identical to query sequence are highlighted in color.

Top 1 final models from D-I-TASSER

Click to view | Ranka | Download | Estimated TM-scoreb
| 1 | model1.pdb.gz | 0.6402
(a) | D-I-TASSER simulations generate a large ensemble of structural conformations, i.e. decoys. These decoys are clustered by SPICKER based on pairwise structure similarity to report up to five final models from the five largest clusters. Models are ranked in descending order of cluster size. If the simulations converge well, it is possible to have less than 5 models generated, which is usually an indication of good model quality.
(b) | The model confidence is quantitatified by estimated TM-score (eTM-score), calculated based on significance of threading template alignments, contact map satisfaction rate, mean absolute error between distance of model and distance of DeepPotential, and convergence of D-I-TASSER simulations. eTM-score is typically in the range of [0, 1], with higher eTM-score signifies higher model confidence.

#### [Click result.zip to download all results on this page]

References:
1. | Wei Zheng, Chengxin Zhang, Yang Li, Robin Pearce, Eric W. Bell, Yang Zhang. Folding non-homology proteins by coupling deep-learning contact maps with I-TASSER assembly simulations. In preparation, 2020.