GO:0098772	F	0.38	molecular function regulator
GO:0005088	F	0.36	Ras guanyl-nucleotide exchange factor activity
GO:0032403	F	0.29	protein complex binding
GO:0019899	F	0.28	enzyme binding
GO:0005102	F	0.27	receptor binding
GO:0004871	F	0.22	signal transducer activity
GO:0004872	F	0.21	receptor activity
GO:1901363	F	0.20	heterocyclic compound binding
GO:0097159	F	0.20	organic cyclic compound binding
GO:0005178	F	0.20	integrin binding
GO:0003824	F	0.20	catalytic activity
GO:0004888	F	0.18	transmembrane signaling receptor activity
GO:0042813	F	0.16	Wnt-activated receptor activity
GO:0016787	F	0.12	hydrolase activity
GO:0003676	F	0.12	nucleic acid binding
GO:0003823	F	0.11	antigen binding
