GO:0003824	F	0.45	catalytic activity
GO:0016740	F	0.37	transferase activity
GO:0022857	F	0.32	transmembrane transporter activity
GO:0019899	F	0.31	enzyme binding
GO:0015075	F	0.31	ion transmembrane transporter activity
GO:0015267	F	0.30	channel activity
GO:0004842	F	0.30	ubiquitin-protein transferase activity
GO:0005216	F	0.29	ion channel activity
GO:1901363	F	0.25	heterocyclic compound binding
GO:0097159	F	0.25	organic cyclic compound binding
GO:0005261	F	0.24	cation channel activity
GO:0046873	F	0.23	metal ion transmembrane transporter activity
GO:0031625	F	0.23	ubiquitin protein ligase binding
GO:0008092	F	0.23	cytoskeletal protein binding
GO:0022836	F	0.20	gated channel activity
GO:0004872	F	0.17	receptor activity
GO:0036094	F	0.16	small molecule binding
GO:0099600	F	0.15	transmembrane receptor activity
GO:0005262	F	0.15	calcium channel activity
GO:0097367	F	0.14	carbohydrate derivative binding
GO:0030674	F	0.14	protein binding, bridging
GO:0004871	F	0.14	signal transducer activity
GO:0032555	F	0.13	purine ribonucleotide binding
GO:0030507	F	0.13	spectrin binding
GO:0008093	F	0.13	cytoskeletal adaptor activity
GO:0035639	F	0.12	purine ribonucleoside triphosphate binding
GO:0032550	F	0.12	purine ribonucleoside binding
GO:0003676	F	0.12	nucleic acid binding
GO:0005524	F	0.11	ATP binding
GO:0005244	F	0.11	voltage-gated ion channel activity
GO:0004888	F	0.11	transmembrane signaling receptor activity
