GO:0097159	F	0.77	organic cyclic compound binding
GO:0004871	F	0.73	signal transducer activity
GO:0003700	F	0.66	transcription factor activity, sequence-specific DNA binding
GO:1901363	F	0.61	heterocyclic compound binding
GO:0004872	F	0.58	receptor activity
GO:0038023	F	0.57	signaling receptor activity
GO:0003676	F	0.57	nucleic acid binding
GO:0003677	F	0.54	DNA binding
GO:0000981	F	0.50	RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003707	F	0.47	steroid hormone receptor activity
GO:0098531	F	0.43	transcription factor activity, direct ligand regulated sequence-specific DNA binding
GO:0004879	F	0.42	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565	F	0.40	sequence-specific DNA binding
GO:0044212	F	0.37	transcription regulatory region DNA binding
GO:0008289	F	0.36	lipid binding
GO:0042562	F	0.32	hormone binding
GO:0005496	F	0.32	steroid binding
GO:0003690	F	0.30	double-stranded DNA binding
GO:0000976	F	0.29	transcription regulatory region sequence-specific DNA binding
GO:0005102	F	0.20	receptor binding
GO:0044877	F	0.19	macromolecular complex binding
GO:1990239	F	0.17	steroid hormone binding
GO:0003682	F	0.17	chromatin binding
GO:0000977	F	0.17	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003824	F	0.15	catalytic activity
GO:0046983	F	0.14	protein dimerization activity
GO:0043167	F	0.14	ion binding
GO:0030284	F	0.14	estrogen receptor activity
GO:0019899	F	0.14	enzyme binding
GO:0000989	F	0.14	transcription factor activity, transcription factor binding
GO:0001228	F	0.13	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0000982	F	0.13	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008134	F	0.12	transcription factor binding
GO:0004883	F	0.12	glucocorticoid receptor activity
GO:0001077	F	0.12	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0000978	F	0.11	RNA polymerase II core promoter proximal region sequence-specific DNA binding
