GO:0003700	F	0.73	transcription factor activity, sequence-specific DNA binding
GO:0097159	F	0.72	organic cyclic compound binding
GO:0004871	F	0.68	signal transducer activity
GO:1901363	F	0.61	heterocyclic compound binding
GO:0003676	F	0.58	nucleic acid binding
GO:0000981	F	0.57	RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003677	F	0.54	DNA binding
GO:0098531	F	0.52	transcription factor activity, direct ligand regulated sequence-specific DNA binding
GO:0004872	F	0.52	receptor activity
GO:0004879	F	0.51	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0038023	F	0.49	signaling receptor activity
GO:0043565	F	0.40	sequence-specific DNA binding
GO:0044212	F	0.35	transcription regulatory region DNA binding
GO:0003690	F	0.31	double-stranded DNA binding
GO:1990837	F	0.30	sequence-specific double-stranded DNA binding
GO:0008289	F	0.29	lipid binding
GO:0000976	F	0.29	transcription regulatory region sequence-specific DNA binding
GO:0003707	F	0.27	steroid hormone receptor activity
GO:0044877	F	0.21	macromolecular complex binding
GO:0043167	F	0.21	ion binding
GO:0008134	F	0.21	transcription factor binding
GO:0005102	F	0.20	receptor binding
GO:0042562	F	0.19	hormone binding
GO:0005496	F	0.19	steroid binding
GO:0003682	F	0.18	chromatin binding
GO:0001012	F	0.17	RNA polymerase II regulatory region DNA binding
GO:0046983	F	0.16	protein dimerization activity
GO:0000977	F	0.16	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0046872	F	0.14	metal ion binding
GO:0019899	F	0.14	enzyme binding
GO:0003824	F	0.14	catalytic activity
GO:0000989	F	0.13	transcription factor activity, transcription factor binding
GO:0030284	F	0.12	estrogen receptor activity
GO:0003708	F	0.12	retinoic acid receptor activity
GO:0046982	F	0.11	protein heterodimerization activity
GO:0042802	F	0.11	identical protein binding
GO:0035257	F	0.11	nuclear hormone receptor binding
GO:0001228	F	0.11	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
