GO:0016787	F	1.00	hydrolase activity
GO:0004112	F	0.99	cyclic-nucleotide phosphodiesterase activity
GO:0004114	F	0.98	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:1901363	F	0.64	heterocyclic compound binding
GO:0097159	F	0.64	organic cyclic compound binding
GO:0097367	F	0.54	carbohydrate derivative binding
GO:0000166	F	0.54	nucleotide binding
GO:0032555	F	0.53	purine ribonucleotide binding
GO:0047555	F	0.44	3',5'-cyclic-GMP phosphodiesterase activity
GO:0030551	F	0.44	cyclic nucleotide binding
GO:0032561	F	0.36	guanyl ribonucleotide binding
GO:0004118	F	0.32	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0030553	F	0.29	cGMP binding
GO:0004115	F	0.29	3',5'-cyclic-AMP phosphodiesterase activity
GO:0032559	F	0.26	adenyl ribonucleotide binding
GO:0043167	F	0.21	ion binding
GO:0046872	F	0.20	metal ion binding
GO:0030552	F	0.20	cAMP binding
GO:0003676	F	0.18	nucleic acid binding
GO:0032550	F	0.16	purine ribonucleoside binding
GO:0035639	F	0.15	purine ribonucleoside triphosphate binding
GO:0008144	F	0.15	drug binding
GO:0003677	F	0.14	DNA binding
