GO:0016787	F	1.00	hydrolase activity
GO:0004112	F	0.99	cyclic-nucleotide phosphodiesterase activity
GO:0004114	F	0.98	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0032555	F	0.56	purine ribonucleotide binding
GO:0030551	F	0.56	cyclic nucleotide binding
GO:0004115	F	0.54	3',5'-cyclic-AMP phosphodiesterase activity
GO:0047555	F	0.40	3',5'-cyclic-GMP phosphodiesterase activity
GO:0030552	F	0.38	cAMP binding
GO:0046872	F	0.36	metal ion binding
GO:0004118	F	0.29	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0030553	F	0.26	cGMP binding
GO:0015631	F	0.26	tubulin binding
GO:0044325	F	0.19	ion channel binding
GO:0019899	F	0.19	enzyme binding
GO:0031690	F	0.18	adrenergic receptor binding
GO:0044389	F	0.17	ubiquitin-like protein ligase binding
GO:0008144	F	0.14	drug binding
GO:0048101	F	0.13	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity
