GO:0005216	F	1.00	ion channel activity
GO:0008324	F	0.99	cation transmembrane transporter activity
GO:0005261	F	0.98	cation channel activity
GO:0015081	F	0.97	sodium ion transmembrane transporter activity
GO:0005272	F	0.96	sodium channel activity
GO:0022836	F	0.91	gated channel activity
GO:0099600	F	0.87	transmembrane receptor activity
GO:0015280	F	0.86	ligand-gated sodium channel activity
GO:0097159	F	0.29	organic cyclic compound binding
GO:1901363	F	0.28	heterocyclic compound binding
GO:0003824	F	0.27	catalytic activity
GO:0000166	F	0.27	nucleotide binding
GO:0046872	F	0.26	metal ion binding
GO:0019904	F	0.25	protein domain specific binding
GO:0050699	F	0.24	WW domain binding
GO:0046914	F	0.16	transition metal ion binding
GO:0035639	F	0.16	purine ribonucleoside triphosphate binding
GO:0032555	F	0.16	purine ribonucleotide binding
GO:0032550	F	0.16	purine ribonucleoside binding
GO:0016491	F	0.15	oxidoreductase activity
GO:0005524	F	0.15	ATP binding
GO:0005244	F	0.14	voltage-gated ion channel activity
GO:0051540	F	0.13	metal cluster binding
GO:0050662	F	0.13	coenzyme binding
GO:0044736	F	0.13	acid-sensing ion channel activity
GO:0016726	F	0.13	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
