GO:0003824	F	1.00	catalytic activity
GO:0003916	F	0.95	DNA topoisomerase activity
GO:1901363	F	0.53	heterocyclic compound binding
GO:0097159	F	0.53	organic cyclic compound binding
GO:0036094	F	0.29	small molecule binding
GO:0000166	F	0.28	nucleotide binding
GO:0035639	F	0.27	purine ribonucleoside triphosphate binding
GO:0032555	F	0.27	purine ribonucleotide binding
GO:0032550	F	0.27	purine ribonucleoside binding
GO:0003676	F	0.27	nucleic acid binding
GO:0005524	F	0.24	ATP binding
GO:0003677	F	0.18	DNA binding
GO:0016787	F	0.14	hydrolase activity
