GO:0019899	F	0.46	enzyme binding
GO:0005102	F	0.35	receptor binding
GO:0003824	F	0.27	catalytic activity
GO:0019901	F	0.26	protein kinase binding
GO:0001540	F	0.25	beta-amyloid binding
GO:0005198	F	0.24	structural molecule activity
GO:1901363	F	0.23	heterocyclic compound binding
GO:0097159	F	0.23	organic cyclic compound binding
GO:0043167	F	0.22	ion binding
GO:0046872	F	0.20	metal ion binding
GO:0003676	F	0.20	nucleic acid binding
GO:0017016	F	0.19	Ras GTPase binding
GO:0030971	F	0.18	receptor tyrosine kinase binding
GO:0098772	F	0.17	molecular function regulator
GO:0017137	F	0.17	Rab GTPase binding
GO:0060090	F	0.16	binding, bridging
GO:0032403	F	0.16	protein complex binding
GO:0030234	F	0.16	enzyme regulator activity
GO:0035591	F	0.15	signaling adaptor activity
GO:0098748	F	0.14	endocytic adaptor activity
GO:0032947	F	0.14	protein complex scaffold
GO:0030276	F	0.14	clathrin binding
GO:0005543	F	0.14	phospholipid binding
GO:0003723	F	0.14	RNA binding
GO:0035615	F	0.13	clathrin adaptor activity
GO:0035612	F	0.13	AP-2 adaptor complex binding
GO:0030695	F	0.13	GTPase regulator activity
GO:0005546	F	0.13	phosphatidylinositol-4,5-bisphosphate binding
GO:0001784	F	0.13	phosphotyrosine binding
GO:0050750	F	0.12	low-density lipoprotein particle receptor binding
GO:0030159	F	0.12	receptor signaling complex scaffold activity
GO:0008134	F	0.12	transcription factor binding
GO:0005096	F	0.11	GTPase activator activity
