GO:0022892	F	0.87	substrate-specific transporter activity
GO:0005262	F	0.86	calcium channel activity
GO:0097159	F	0.40	organic cyclic compound binding
GO:1901363	F	0.38	heterocyclic compound binding
GO:0098772	F	0.30	molecular function regulator
GO:0036094	F	0.29	small molecule binding
GO:0005085	F	0.29	guanyl-nucleotide exchange factor activity
GO:0017112	F	0.28	Rab guanyl-nucleotide exchange factor activity
GO:0000166	F	0.28	nucleotide binding
GO:0032555	F	0.24	purine ribonucleotide binding
GO:0032550	F	0.24	purine ribonucleoside binding
GO:0035639	F	0.23	purine ribonucleoside triphosphate binding
GO:0003824	F	0.16	catalytic activity
GO:0005524	F	0.13	ATP binding
GO:0046872	F	0.11	metal ion binding
GO:0032561	F	0.11	guanyl ribonucleotide binding
