GO:0004871	F	0.53	signal transducer activity
GO:1901363	F	0.52	heterocyclic compound binding
GO:0097159	F	0.52	organic cyclic compound binding
GO:0038023	F	0.50	signaling receptor activity
GO:0003824	F	0.50	catalytic activity
GO:0004673	F	0.39	protein histidine kinase activity
GO:0046872	F	0.36	metal ion binding
GO:0035639	F	0.31	purine ribonucleoside triphosphate binding
GO:0032559	F	0.31	adenyl ribonucleotide binding
GO:0032550	F	0.31	purine ribonucleoside binding
GO:0003677	F	0.30	DNA binding
GO:0016787	F	0.18	hydrolase activity
GO:0044729	F	0.17	hemi-methylated DNA-binding
GO:0008270	F	0.15	zinc ion binding
GO:0005509	F	0.14	calcium ion binding
