D-I-TASSER Q8NEM7-D1

D-I-TASSER results for Q8NEM7-D1

[Click result.zip to download all results on this page]

Input Sequence in FASTA format

>Q8NEM7 (779 residues)
MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKKLRRN
VNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEEL
PPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHSI
TSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFKR
YSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCNL
AIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLGD
PLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKCP
VKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGNY
FTPQQTSSFLKSPTPPPSSKPSSIPRKSSVDLNQVSMLSPAALSPASSSQRTTATQVMAN
SAGLNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINLSGLLPSGGLLPNALPSAMQ
AASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQ
PGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFMQSQAAVLSQLGSAENRPEQSLPQQRF
QLSSAFQQQQQQIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTPKF

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEELPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFKRYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCNLAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLGDPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKCPVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGNYFTPQQTSSFLKSPTPPPSSKPSSIPRKSSVDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFMQSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQQQQQQIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTPKF
Prediction	CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCSSSSSCCCCCCSSSSCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCSSCCSSSSSSSSCCCCCCCCCCCCCSSSSSSCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCHHHHCCCCCCCCCCSHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Confidence	80599999999999999986268887766655542668999999999744776334300146888876403677159996047874154226777765543036743479999998487978999998752787111564899985235788889987641489844763679999999853688998899999999999961687667998336777776665553147764013221024001145664156899988711012322103578776665667777888877788888899986674441234677788888988777654567742235678865421114225789977577657887877666778888889888876656888778565565444445677878877778888877767889988888898777688888888888999887888888788888889988888888989999999998888998888888878998889988888899999878998878888778888887888898988899998888888788887899998999999998999999888878888997898878899987678899987777888888899999989999999889899988988888877466667788888789988878888888889998899998888988899888878888788887777878888899999889888888889999999999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEELPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFKRYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCNLAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLGDPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKCPVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGNYFTPQQTSSFLKSPTPPPSSKPSSIPRKSSVDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFMQSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQQQQQQIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTPKF
Prediction	64420440053043004205632464544453241024202400142046415455232103103411544411000010102340000114345424444131114442004103633001100420453402000000000000010404646443230100000011100130031015534402341013002300300232010214120121023122344415244243214424443343455356214342120131034337454454243413535531432334416152155141541143453364643423114254045511031255352240111013313213112403245466554543434212364334303134524254335224521466254434144344444334433344445435444353444454454441445344444444444423122344444324433444444334544443444443334424144344443443443543424334344432322434444424243434424243444444324444314432444444323432341442423313434441232444445223234444444442442644423213344443324325244343233334244444411212232423434454354441434334444324444344544322432424434334441434423444444446724344256
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Contact, Hydrogen and Distance Map Used in D-I-TASSER simulation

Contact Map

Distance Map

Hydrogen bond networks

D-I-TASSER simulation is guided by the consensus contact map (left figure), distance map (middle figure) and Hydrogen bond network (right figure) derived based on confidence scores of DeepPotential. In the contact, distance map and hydrogen bond networks, the axes mark the residue index along the sequence. For the contact map, each dot represents a residue pair with predicted contact, while for the distance map and hydrogen bond network, a color scale represents a distance of 1-20+ angstroms or a angle of 0-180 degree.

Top 10 threading templates used by D-I-TASSER

Rank

PDB
hit

ID1

ID2

Cov

Norm.
Zscore

Download
alignment

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480                 500                 520                 540                 560                 580                 600                 620                 640                 660                 680                 700                 720                 740                 760

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

SS
Seq

CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCSSSSSCCCCCCSSSSCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCSSCCSSSSSSSSCCCCCCCCCCCCCSSSSSSCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCHHHHCCCCCCCCCCSHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEELPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFKRYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCNLAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLGDPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKCPVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGNYFTPQQTSSFLKSPTPPPSSKPSSIPRKSSVDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFMQSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQQQQQQIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTPKF

5ganJ

0.05

0.04

2.06

1.05

EigenThreader

LNKLTEEREKLLVNKPNAATDALSYLKDLENDRVNSDLQKMRTILKSYRKADP--TNPQGWIASARLEEKARKF------------------------------SVAKKIIENGCQECPRSSDIWLENIRLHE---------------------------------SDVHYCKTLVATAINFN--PTSPLLWFKAIDLE-----------STTVNKYRVVRKALQEIPRDEGLWKLAVSFEAQVIKMLEKATQFIPQSMDLLTAYTNLQSNAKMTLNSFRKILPQEPEIWIISTLLEERNNPKLVSLLKEGLLELSKNGYKATLSAWLKRAEALNDA--------------------PNSNLTCQAIVYAILEWLRESGEYEILEKMPHSKVQIAVLKKLIQWDPSRLKMATESYEELLAFFQELLFQTSDDIRANMREKSPGLLMMYVSEYWKAQKGDTRQTLVLIDQIIDFAPHNLDLRFFKIKLLGRSLQLDELRDFFQQTFSSLEDFKISGTERLYYKYVNFLRYQDLNEEAIKFLNERCLK----SFPICHKFFLQLGQIYHSMGNIEMSRETYLSGTRLVPNCPLLWVSLSKIDEIDLKNPVRARSILDRGLLKN-----PDD----VLFYIAKIQMEIRLGNLDQAELLVTQALQKFPSNALLWVEQIKLFKHGN------KSSLKKTIFQDALRRTQNDHRVLLEIGVSFYAEAQYETSLKWLERALKKCTWVWLFRTYARLGKYNMFDQCEPTYGPEWIAASKNCTPREI

4btgA

0.13

0.10

3.61

1.27

SPARKS-K

VGKGNIDPVMYARLFFQYAQAG---------GALSV-DELVNQFTEYHQSTACNPE------IWRKLTAYITGS--------SNR----AIKADAVG-----KVPPTAEQLRTLSEHELFHHITTDFVCHVLSPL-------------GFILPDAAYVYRVGRTATYPNFYALVDCVRASDLRR---------ML---TALSSVDSGALAPA----LISQHLANARGNFDANAVVSSVLTISTP--------KELDPSARLQLRSNLAQDMVKQRG-RAEVIFSDEELSST---------IIPWFIEMSEVS-----------PFKLRPINETTSYIGQTSAIDHMGQPSHVVVYEDWQFAKEITAFTPVKLANNSNQRFLDVEPGISDRMSATLIGNTFAVSAFVKNRTAVYE---------------------AVSQRGT----------------VNGAEMTLGFPSVVERDYALDR-DPMVAIAALRTGIVDESLEARASNDLKRSMFNYYAAVMHYAVAHNPEVV---VSEHQGVAAEQGSLYLVWNVRTELRIPVGYNAIEGGSIRTPEPAYNKPIQ--PSEVLQAKVLDHEASTEFAYEDAYSVTIRNKRYTAEVVRILKPTVAHAIIQMWYSWFVEDDRTLAAARRTS----RDDAEKLAIDGRRMQNAVLRKIEMIGTTGIG----ASAVHLAQSRIVDQMAGRGLSSDLHVGINRHRIRIWAGLAVLQMMGLLSRSEAEALTKVLGDSNALGMVVA-------------

2zxqA

0.05

2.16

1.47

MapAlign

--------ASETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDKIDAVITVQITVKHLNVTKIKNNLDYTYGFISGAGLSAGRGGSQNTRVYATTQQTGDATSLGWYYHRTVTDSKGKKYTVAETRDIMNNPYKSEEVPEFGSQAQNPFLTTLDNVKKVALNTYGDIGQRLGGADDMNTMMEEGSKYGARFVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKM--------INDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANGGYNMKDFEGWQGRNVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVV---------------VSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQ------------------------------------KLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFVRIVENQYSGITYEKDGTLKSLTNNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMK-----

6tb4F

0.21

0.05

1.64

4.84

HHsearch

------------------------------------------------------KFAETSEEILHKY--EKFPPSLTFHIHENH--YRFGD--QD-----GV-IPKNSKAFLEYVAREEIPPALIEVTKDAGVQ-LYEGCIILRIYDHRK----------TYTTILRPTQLSLYADLLYQTDYQVRFTDSLSLNIETEILTASKRNLDLSVPLNPHRATANLKPEVPYYDPDTVVHEHRPDARGNMSDYERLMLLL-SDRFMRLRFVEA-----------------------WRKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

6vbu7

0.09

0.08

3.00

0.69

CEthreader

--------------------------------DLNLNRADYLQVGVTSQKTMKLLPARATQKVVMCFGMKKGEAVTVFKTLPGQKIARLELGGALNTPQEKIFIAAG-SEIRGFTKRGKQFLSFETNLTESIKAMHISGSDLFLSASY-IYNHYCDCKDQHYYLSGDKINDVICLPVERLLREVPVLACQDRVLRVLQGSDVTYEIEVPGPPTVLALHNGNGGDSGEDL---------------------------------------------------LFGTSDGKLGLIQITTSKPIHKWEIRNEKKRGGILCVDSFDIVGDGVKDLLVGRDDGMVEVYGFDNANEPVLRFDHTLSESVTSIQGGCVGKDGYDE----IVVSTYSGWITGLTTEPNQEMQNKISSLRSELEQLQYKVLQEREKYQQSSQSSKAKSAVPSFSVNDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQANTTRLELKIRSIEGQYGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFSELHSWVVFCMPEVPEKPPAGECVT--FYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQVHEGNTNFLIPEYRCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQNALIAFFD

4ui9O

0.09

0.07

2.71

0.97

EigenThreader

------------------------------KDWVTPYKIAVLVLLSEMSRTGEGAVSLVERRRLNQQLLPLLQG------------------------------PDITVSKLLKLIEESCPQIRIKLMAEGE---------------------------------LKDMEQFFDDLSDSFSGPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQSDENKKPLSQKQAEFFLSQQASLLKND----ETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQ--------DVFSSTHSLLHYFDRLILTGAESKSNGEEG---------------------------YGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEQQNNTESFAVALCHLAELHAEQERFPPNSQH----AQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLK----NTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQL-----ILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYAEALEAAIENLNEAKNYFAKVDCKQELPSVPLINHL----------

6t9iB

0.18

0.05

1.55

0.82

FFAS-3D

-------------------------------------------------RPKRLYNFVEDASILKKY--EQYLHSFEFHIYENN----YKICAPAGLILT----KNNEKEFLEYVARGRIPDAIMEVLRDCNIQ-FYEGNLILQVYDHTNTVDVRP---RVYRTLLKPNDLTTYYDMMSY-ADNARFSDSIYQQFESEILTLTKRNLSLSVPLNPYEHRDMLAFSEPHWDSEKKSFIHENYEQLMLITNSTFAVSLTKNQFSRLKFIEQWRINK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3j3iA

0.11

0.10

3.57

1.18

SPARKS-K

FGRQIASLLQYFENIIACYQIYGDIDRDPAFGENTMRAKLVNDVAKSTGWNQQVQKFPNRMDSLISLLEQMQTGQ--SKLTRLVKGFLILLMAERKEVDFHVGNHYAIAPVCDSYDSEAHAAVLLAMCREYHVSVPADACIVS-----QGRQIQPGSA-----VTLNPGL--VYSSILTYAMDTS-CTDL----LQEAQIIACSSRIGL-PTVVLSKAVGRVHQMLGMVAAKDIISATHMQSRTGFDPSHGIRQYLNSNSRLVT----QMASKLTGIGLFDATPQMRIFSEMDTADYADMLHLTIFEGLWLVDASVCTDNGPISFLV--------------------NGEKLLSADRAGYDVLVEELTLAN----------IRIEHHKMPTGAFTTRWVAKRDSALRLTP---RSRTAHRVDMVRECDFNPTMNLRLRGSGVKSRRRVSEVAHVF-----RSPPRRESTTTTDDSPRWLTREGPQLTRRVPIIDEPPAYESG----RSSSPVTSSISEGTSQHEEEMGLFDAEELPMQQTVIATEARRRLGTLERIQEAALEGAEKNRRIEAMLSARDPQFTGREQITKMLSDGGLGVLELVDKTVGVKGLKEVRSIDGIEGFAVVRTLLSGNSKHVRRINQLIRESNPSAFETEAS------RMRRLRADWDGDAGSAPVNAVGNSPGWKRWLENNNIPSDIQVAGKKRMCSYLAEVLSHGNLKLSD-------ATKLGFPPQLSSEEFSTCSEATLAWRNAPSSLGVRPFAQEDSRW

2jg4A

0.11

0.03

1.24

0.78

CNFpred

LKEALDVTLPRLKAFIPQLLSRLHIEALLHGNIKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNVHNNCGIEIYY------QTDMQSTSENMFLELFC-QIISEPCFNTLRTKEQLGFIVFSGPRRAN-----------GIQGLRFIIQSLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKP---KKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTL--------------TKEDIIKFYKEML----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5l5kA

0.07

0.04

1.50

0.50

DEthreader

--P-SFVTF--VVDTGHIYKLSS------------LIDYKENRLILLRLEDLFKLGEPFHSGVFGVIVSYNDDKLFIATAVDGKPFPTISSRKTYVFHASMIKIPTFIDFDIYYFLTLQTSKLVRLCKEDTAFSY----LQAAYLSK-------R-LGVRPDDDLLFT----VF-S---KRK--M-KSLDESALCTEDRMTSVIAYSLAFKHEVEHTRKERCERSRE-RR-----PELSAGVNDGLVIQIQCYSPAAKEVPRIITENGDHHV-------------------------------------------------------------------------------------------------------------------------------------------------NCSVHN-S-------CLSCVESRCHWCKYRHV-GRVKLPED--QLLRVDKIILNIQGIEQRVPARFNSSSVQCQNTSYSY-EGMEINNLPVEL----------VYLYKCGAMRESCGLCLK--------------NPRITEIIPV-----------TIR-ENLGLEFRDIASHVKVA-------------------------IPAEQIVC--EMGEAKPSQHAGFVSQLYYFMTL----------------------------NAGSNVVFHRRSPSY-----------------T-QVDRARIRQDLVF----------------------------------------------------

(a)	ID1 is the number of template residues identical to query divided by number of aligned residues.
(b)	ID2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment and is highlighted in bold.
(e)	Download alignment lists the threading program used to identify the template, and provide the 3D structure of aligned regions of threading templates (threading[1-10].pdb.gz).
(f)	Template residues identical to query sequence are highlighted in color.

Top 1 final models from D-I-TASSER

Click to view	Rank^a	Download	Estimated TM-score^b
	1	model1.pdb.gz	0.5

(a)

D-I-TASSER simulations generate a large ensemble of structural conformations, i.e. decoys. These decoys are clustered by SPICKER based on pairwise structure similarity to report up to five final models from the five largest clusters. Models are ranked in descending order of cluster size. If the simulations converge well, it is possible to have less than 5 models generated, which is usually an indication of good model quality.

(b)

The model confidence is quantitatified by estimated TM-score (eTM-score), calculated based on significance of threading template alignments, contact map satisfaction rate, mean absolute error between distance of model and distance of DeepPotential, and convergence of D-I-TASSER simulations. eTM-score is typically in the range of [0, 1], with higher eTM-score signifies higher model confidence.

[Click result.zip to download all results on this page]

References:
1.	Wei Zheng, Chengxin Zhang, Yang Li, Robin Pearce, Eric W. Bell, Yang Zhang. Folding non-homology proteins by coupling deep-learning contact maps with I-TASSER assembly simulations. In preparation, 2020.