GO:0098772	F	0.97	molecular function regulator
GO:0005085	F	0.93	guanyl-nucleotide exchange factor activity
GO:0005088	F	0.79	Ras guanyl-nucleotide exchange factor activity
GO:0022857	F	0.40	transmembrane transporter activity
GO:0005244	F	0.39	voltage-gated ion channel activity
GO:0005245	F	0.37	voltage-gated calcium channel activity
GO:0019899	F	0.25	enzyme binding
GO:1901363	F	0.23	heterocyclic compound binding
GO:0097159	F	0.23	organic cyclic compound binding
GO:0043167	F	0.23	ion binding
GO:0017016	F	0.22	Ras GTPase binding
GO:0017034	F	0.21	Rap guanyl-nucleotide exchange factor activity
GO:0032555	F	0.20	purine ribonucleotide binding
GO:0043169	F	0.16	cation binding
GO:0046872	F	0.15	metal ion binding
GO:0035639	F	0.15	purine ribonucleoside triphosphate binding
GO:0032550	F	0.15	purine ribonucleoside binding
GO:0030234	F	0.15	enzyme regulator activity
GO:0003824	F	0.14	catalytic activity
GO:0030695	F	0.13	GTPase regulator activity
GO:0008289	F	0.13	lipid binding
GO:0004871	F	0.13	signal transducer activity
GO:0030742	F	0.12	GTP-dependent protein binding
GO:0008047	F	0.12	enzyme activator activity
GO:0032561	F	0.11	guanyl ribonucleotide binding
GO:0032559	F	0.11	adenyl ribonucleotide binding
GO:0019992	F	0.11	diacylglycerol binding
GO:0005096	F	0.11	GTPase activator activity
