GO:0003824	F	0.76	catalytic activity
GO:1901363	F	0.67	heterocyclic compound binding
GO:0097159	F	0.67	organic cyclic compound binding
GO:0019787	F	0.62	ubiquitin-like protein transferase activity
GO:0004842	F	0.61	ubiquitin-protein transferase activity
GO:0003676	F	0.61	nucleic acid binding
GO:0000166	F	0.36	nucleotide binding
GO:0035639	F	0.35	purine ribonucleoside triphosphate binding
GO:0032555	F	0.35	purine ribonucleotide binding
GO:0032550	F	0.35	purine ribonucleoside binding
GO:0004871	F	0.34	signal transducer activity
GO:0032559	F	0.33	adenyl ribonucleotide binding
GO:0016787	F	0.31	hydrolase activity
GO:0004872	F	0.31	receptor activity
GO:0038023	F	0.29	signaling receptor activity
GO:0017111	F	0.28	nucleoside-triphosphatase activity
GO:0008329	F	0.28	signaling pattern recognition receptor activity
GO:0046872	F	0.26	metal ion binding
GO:0046914	F	0.18	transition metal ion binding
GO:0008270	F	0.17	zinc ion binding
GO:0003677	F	0.17	DNA binding
GO:0042802	F	0.16	identical protein binding
GO:0019899	F	0.14	enzyme binding
GO:0003723	F	0.12	RNA binding
GO:0030674	F	0.11	protein binding, bridging
