GO:0030674	F	0.34	protein binding, bridging
GO:0098772	F	0.33	molecular function regulator
GO:0003824	F	0.29	catalytic activity
GO:0035591	F	0.28	signaling adaptor activity
GO:0005070	F	0.26	SH3/SH2 adaptor activity
GO:0005085	F	0.21	guanyl-nucleotide exchange factor activity
GO:0043167	F	0.18	ion binding
GO:0005086	F	0.18	ARF guanyl-nucleotide exchange factor activity
GO:0030695	F	0.15	GTPase regulator activity
GO:0019899	F	0.15	enzyme binding
GO:0005543	F	0.15	phospholipid binding
GO:0005096	F	0.14	GTPase activator activity
GO:1901363	F	0.13	heterocyclic compound binding
GO:0097159	F	0.13	organic cyclic compound binding
GO:0035091	F	0.13	phosphatidylinositol binding
GO:0022892	F	0.13	substrate-specific transporter activity
GO:0004601	F	0.13	peroxidase activity
GO:0046872	F	0.12	metal ion binding
GO:0004871	F	0.12	signal transducer activity
GO:1901981	F	0.11	phosphatidylinositol phosphate binding
GO:0005344	F	0.11	oxygen transporter activity
