GO:0019899	F	0.45	enzyme binding
GO:0098772	F	0.41	molecular function regulator
GO:0005085	F	0.37	guanyl-nucleotide exchange factor activity
GO:0005102	F	0.36	receptor binding
GO:0019901	F	0.35	protein kinase binding
GO:0030971	F	0.33	receptor tyrosine kinase binding
GO:0019904	F	0.31	protein domain specific binding
GO:0017124	F	0.30	SH3 domain binding
GO:1901363	F	0.25	heterocyclic compound binding
GO:0097159	F	0.25	organic cyclic compound binding
GO:0036094	F	0.22	small molecule binding
GO:0032555	F	0.21	purine ribonucleotide binding
GO:0032550	F	0.21	purine ribonucleoside binding
GO:0035639	F	0.20	purine ribonucleoside triphosphate binding
GO:0044877	F	0.15	macromolecular complex binding
GO:0032561	F	0.15	guanyl ribonucleotide binding
GO:0032403	F	0.14	protein complex binding
GO:0005525	F	0.14	GTP binding
GO:0043167	F	0.12	ion binding
